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…   For years, researchers have known that many datasets miss a key …

… CRAGE-CRISPR combo helps further demystify biosynthetic gene clusters.  The Science Microbial … active secondary metabolites and helping them identify and describe the functions of the biosynthetic gene … highly regulated in bacteria, making it difficult to identify which pathway corresponds to which metabolite. Finding a …

… dwell in herbivore guts and help them digest their last leafy meal. In their evolutionary history, these fungi branched … proposal. The next step for the team was to try to identify what natural products the fungi were making. So, Trent … known to be made only by aerobic fungi. In order to identify more of the fungal natural products, O’Malley and her …

… more than once, and these events took place a million years apart: the individual with a maternal  B. distachyon parent (D plastotype) some 1.4 million years ago (Mya), while the S plastotype was a more recent … anticipated with only minor gene loss even after a million years.” Reference genomes for  B. distachyon ,  B. stacei …

… a dark room with a flashlight, only able to clearly identify what falls within that single beam. When it comes to … but we knew the families,” Kyrpides said. Yet, “almost 20 years of metagenomic data and metagenomic analysis, and … families. From there they focused on families with at least 100 members.  “If you have 100 sequences, the quality of the …

… in, on, and around the planet remain unknown. In recent years, advances in sequencing technologies and bioinformatic … diverse than those within more moderate ecosystems. A few years ago, a candidate bacterial lineage was identified from … work was also sponsored by NSF grants DEB-1441717, OCE-1335810, and OIA-1826734 to RS. …