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New and Improved: Eucalyptus Reference is Now Accessible
… assembly to support targeted tree breeding for the bioeconomy.   The Science Researchers report a new reference genome for eucalyptus in the July edition of the journal G3 Genes | Genomes | Genetics , with … inherited from each parent. It also has 700-fold greater contiguity, meaning the genome is reconstructed in much …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… As SIP experiments shed more light on microbial communities than ever before — especially with … work to create FAIR datasets to maximize returns on these advances. Over the last two decades, Stable Isotope … of stable, heavy isotopes, SIP allows researchers to go beyond understanding which microbes are present in a sample, to …
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Making a Lichen Together
… clearly. The Science The humble lichen is a superorganism: one being that is actually comprised of two (or more) participants. One is a fungus (usually belonging to the ascomycetes, one of the two main branches of … (for DNA sequencing and assembly); by a three-year subcontract to DA, FL, and FD (for bioinformatics) from a DOE …
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Taking Stock of the Known and Unknown Microbial Space
… of Science User Facility located at Lawrence Berkeley National Laboratory Berkeley Lab), have taken stock of the … the past three decades, their study assesses what fraction of the microbial diversity we know about, and proposes a … is still unknown.  “We took a deep dive into over 1.8 million bacterial and archaeal genomes to see how much of their …
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Gene Expression: From On-Off Switch to Dial
… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science … a more nuanced library approach to tuning gene expression in metabolic pathways. Compared to the traditional way, which leverages an all-or-nothing approach to … No. FA9550-14-1-0089, the Camille and Henry Dreyfus Foundation, and the JGI Synthesis Program under FP00005685. In …
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The More the Merrier: Making the Case for Plant Pan-genomes
… Brachypodium model system traces polyploid genome evolution. Flowering plants abide by the concept, “the more the merrier,” with respect to their … their base state, they are diploids with two genome copies, one from each parent. Having three or more genome copies …
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Fishing for Novel Cellulose Degraders
… single-cell genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is … of Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab). Using a single-cell screen, they can now identify microbes with specific functional characteristics. When they tested the screen method on …
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How to Target a Microbial Needle within a Community Haystack
… make-up of specific uncultivated microbes from complex environmental samples. The Science A team led by researchers at … targeted genomic approach would allow researchers to focus on specific microbes within metagenome samples and associate … their sequences with their roles within their environments. Summary The traditional shotgun metagenomics …
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Extracting the Secrets of Secondary Metabolites
… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE … with CRISPR provides researchers with a powerful addition to their toolkit to study gene function. As a …
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Mining Metagenomes for Cas Proteins
… to accurately edit genomes (that is, repair gene mutations, and either delete or add genes in a precise fashion) has applications across many areas. In particular, gene editing is being … The work conducted by the US Department of Energy Joint Genome … the Office of Science of the US Department of Energy under contract no. DE-AC02-05CH11231. The work was supported in …
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The Expanding Universe of Methane Metabolisms in Archaea
… Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key role in determining the composition of the Earth’s atmosphere and regulating the global … of Science User Facility located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in …
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Honey Bee Gut Microbiota Divvy Up Dinner
… Scientists find bee gut microbes have a division of labor when it comes to metabolizing complex polysaccharides. Honey bees are invaluable pollinators — cupids of the plant … facilitating the remixing of genes in the next generation of flowering vegetation. In return for their services, …
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