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… After studying the mechanism of action of antifungal natural products and their derivatives during … at the DOE Joint Genome Institute in 2004. The main object of her research was the symbiont community of a gutless … is the Microbial Science Program Head as well as our Deputy of User Programs. Click to learn more about the program's …

… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … have uncovered genomes for just a small fraction of Earth’s microbial diversity. Because most microbes cannot … “It’s a dataset that is going to facilitate many more studies subsequently. And I hope JGI and other institutions …

… technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo PhD, Biotechnology, University of Tokyo … Udwary DW, Mouncey NJ. Comparative and pangenomic analysis of the genus Streptomyces. Sci Rep. 2022 Nov 7;12(1):18909. …

… Nottingham University, UK PhD in Genomics, University of Cambridge, UK Postdoctoral training Wellcome Trust Sanger … Price et al 2018. Mutant phenotypes for thousands of bacterial genes of unknown function. Nature 557:503-509. Blow et al 2016. …

… get any sunlight, and yet they still support a unique array of microorganisms adapted to living in extreme conditions. … five oceanic regions. In doing so, they found a high degree of variability in the types of microorganisms that inhabit these sites, as well as the …

… data set will help identify how different elements of the ecosystem interact and respond to changes in the … their genetic diversity. They hold economic value as both biofuel feedstock and their role in carbon sequestration. Poplar trees grow quickly in a variety of ecosystems and contribute to stabilizing streambanks, …

… The Science Within the archaeal domain, there is a group of tiny hitchhikers. These organisms are abundant and yet … mini genomes to match. As a result, they cannot process all of the chemicals they need to survive. To fill in their nutrient gaps, they must latch onto a larger host — often, a fellow archaeal microbe. Understanding how these …

… and researchers more about the patterns and functions of environmental microbes. Researchers can use the tool to correlate protein annotations with ratios of DNA sequence fragments from the ecosystems. Selecting a … The Impact The initial analysis highlights abundances of gene annotations that provide insights into the nutrients …

… — making it difficult to grasp a deeper understanding of fundamental aspects of fern biology and, more broadly, land plant evolution. … findings in Ceratopteris richardii show a long history of dynamic evolution and rapid changes in both genome … The work conducted by the US Department of Energy Joint Genome Institute is supported by the Office …

… Miscanthus  sequence offers insights into benefits of polyploidy and perenniality. The Science A reference … grass Miscanthus sinensis has been published. Analysis of the genome sequence also provides insights into how the … Innovation, which is supported by the U.S. Department of Energy, Office of Science, Office of Biological and …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … place in evolutionary history. Retaining ancestral features of both plant and animal cells, it shares nearly 7,000 genes …