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Webinar: SIP technologies at EMSL and JGI
… and the JGI’s Rex Malmstrom provided background on the various isotope-related technologies available at JGI and EMSL … least a microgram of DNA in the tube so you’d need at least 2 micrograms in the sample to start with. 2. Q: What would a … C13 and sort of the isotope of proteomics, what about doing this with metabolites at EMSL? A:  The answer to …
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Tracing the Evolution of Shiitake Mushrooms
… highlight the diversity of white rot fungi in the genus Lentinula   The Science Shiitake mushrooms get their name from the same place they often … from around the world. By complete sequencing of 24 new mushroom genomes, and assembling genomes from 60 … work (proposal:10.46936/10.25585/60001048) conducted by the US Department of Energy JGI (https://ror.org/04xm1d337), a …
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The Essential Role of the N-Terminal Domain of the Orange Carotenoid Protein in Cyanobacterial Photoprotection: Importance of a Positive Charge for Phycobilisome Binding
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A Natural Mechanism Can Turbocharge Viral Evolution
… The Science The first step in the deadly dance between a virus and microbial cell is an embrace. For a virus with a “head-tail” morphology, this means using proteins … the discovery of more than 30,000 DGRs in this analysis, a 20-fold increase over what was previously known, throws open …
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Fishing for Novel Cellulose Degraders
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … and unknown. The challenge remains to learn more about what microbes are present in any given … spectrometry-based enzyme activity assay. The work was  reported in  The ISME Journal . While the screen caught …
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Taking Stock of the Known and Unknown Microbial Space
… to the global research community.  Published January 17, 2025 in Science Advances , researchers at the U.S. … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … assesses what fraction of the microbial diversity we know about, and proposes a path forward to curate and cultivate …
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DOE JGI Interns Share Their Summer Experiences
… part of the DOE JGI’s efforts to promote diversity and inclusion in the sciences, among the interns were two … groups, respectively. Each of the interns spoke briefly about their time at the JGI at … with T.B.K. Reddy on the Genomes OnLine Database; Sarah Fruchart , who worked with Matt Blow; Sean Bray , who also …
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Partnerships: Myco-Ed
… ~50 lineages selected for sequencing 16 genomes released 20 members from 15 institutions 300+ students 800+ … analysis.  MycoCosm provides data and tools via a graphical user interface, ensuring that no programming knowledge or … is required to perform computational analyses. The Mycocosm user interface is designed for use by mycologists and …
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Biotech Partners Summer Intern Co-Authors NAR Paper
… Kaushal Sharma, one of five Antioch High School rising juniors … reviewed and assigned NCBI taxonomy name and IDs for nearly 20,000 public/private mtagenome biosamples in GOLD. “Besides … tasks we assigned.”       Click here to watch a video about the Biotech Partner summer interns at the JGI. What …
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Viruses Reprogram Cells into Different Virocells
… Microbial cells infected by viruses undergo metabolic reprogramming. The Science If it … cells as virocells, a change in name first described in 2011 which reflects the metabolic changes they’ve undergone. … ocean could fix less carbon when infected. Little is known about virus-infected microbial cells that are transformed …
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Better Genome Editing for Bioenergy
… of the genes in a lipid-prolific yeast. The Impact The team used this set of guide RNAs on  Yarrowia lipolytica to … furthers the U.S. Department of Energy’s goal of producing sustainable fuels from alternative sources. Moreover, the … CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, but these …
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Biodesign
… The team has three subgroups: Synthetic Biology Lab : a user science group dedicated to user project design, assembly, and quality control Strain … Engineering Group : a research & development group and focused on new technologies and optimizing tools — including …
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