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Better Genome Editing for Bioenergy
… of the genes in a lipid-prolific yeast. The Impact The team used this set of guide RNAs on  Yarrowia lipolytica to … furthers the U.S. Department of Energy’s goal of producing sustainable fuels from alternative sources. Moreover, the team says the approach they used to validate their set of guide RNAs could be applied to …
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Introducing New Members of the JGI User Executive Committee
The JGI welcomes three new members to their User Executive Committee (UEC) – Jack Gilbert, Ashley Shade, and Jason Stajich! They join six other JGI users already serving on the UEC – go here to view the full … community outreach efforts with diversity, equity and inclusion in mind. Microbiome ecologist Shade became Director of …
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JGI@25: Solving the Mystery of the Missing Oil
… between.” To find an explanation, his team tracked the thousands of bacterial and archaeal species using a DNA-based array developed at Berkeley Lab. Over the …
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A One-Stop Shop for Analyzing Algal Genomes
… an interactive browser that allows algal scientists and enthusiasts to look deep into more than 100 algal genomes, … genetic underpinnings responsible for these traits takes us closer to harnessing algae for bioenergy and the greater … genomic data on algae into one place, PhycoCosm allows users to easily compile data that answers what genes are …
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Triggering Morel Fruiting
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility,  reported on just how morel fruiting is triggered when … The JGI provides integrated high-throughput sequencing and computational analysis that enable systems-based scientific …
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Hiroshi Otani
… particularly actinomycetes. His research activity is focused on developing and implementing new technologies and … Mouncey NJ. Comparative and pangenomic analysis of the genus Streptomyces. Sci Rep. 2022 Nov 7;12(1):18909. Otani H, … trove of microbial natural products. Nat Rev Microbiol. 2021 Nov;19(11):683. Mouncey NJ, Otani H, Udwary D, …
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The Expanding Universe of Methane Metabolisms in Archaea
… insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, for publicly available metagenome data … The JGI provides integrated high-throughput sequencing and computational analysis that enable systems-based scientific …
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Learning to Look
Machine learning approach significantly expands inovirus diversity. To answer the question, “Where’s Waldo?” … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, developed an algorithm that a computer could … The JGI provides integrated high-throughput sequencing and computational analysis that enable systems-based scientific …
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Gut Fungi: Unexpected Source of Novel Chemicals
… off early from aerobic fungi, which can breathe oxygen — just like we do. Oxygen is a rich source of energy, and because anaerobic fungi can’t harness it, scientists long held … Neocallimastix californiae , and Piromyces finnis . In work reported in 2017, the fungal genomes were sequenced by the …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do anything, they must find a host, and not just any host will do. It must be a …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
… novel technique to access high-quality genomic information using minute quantities of DNA derived from individual … Other firsts followed. The next year, the JGI team reported the first closed and finished genome derived from … microbial genomes that were mapped to nearly 30 major previously uncharted branches of the tree of life. Used in tandem …
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An Integrated Dataset to Understand Ecosystem Interaction
… time. By collecting data from 27 different poplar ( Populus trichocarpa ) trees, as well as the soil surrounding … wildlife habitats and water-quality regulation. Focusing on the rhizosphere and interactions between the trees, … to conduct a wide variety of analyses that contribute to a sustainable bioeconomy. Summary The 27 samples studied by …
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