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Data Discovery Tool Helps Identify Microbial Roles within Metagenomes
… and researchers more about the patterns and functions of environmental microbes. Researchers can use the tool to correlate protein annotations with ratios of DNA sequence fragments from the ecosystems. Selecting a … The Impact The initial analysis highlights abundances of gene annotations that provide insights into the nutrients …
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Axel Visel
… Programs, he focuses on the development and implementation of strategic initiatives at the JGI. Dr. Visel received his … methods for elucidating the gene regulatory landscape of vertebrate genomes, which led to the discovery of thousands of genetic switches implicated in developmental …
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The More the Merrier: Making the Case for Plant Pan-genomes
… plants; at least once during their evolution, the genomes of flowering plants multiply. Over time, plants lose many … genomes to a diploid state while retaining multiple copies of some genes. This polyploidization process is ongoing and … polyploidy in plants, researchers have sought to learn the origins, evolution and development of plant polyploids. A …
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Evolution of a Fungal Gene Expression Regulator
… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The … themselves can also be modified. The best-known example of a modified DNA base is a methylation of the base cytosine at the 5th position on its carbon ring, … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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JGI@25: Studying Sorghum’s Survival Skills
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … reference genome for Sorghum bicolor . Since then, 2,993 publications, 107 patent applications, and 53 patents have cited that genome. Since publishing that original reference genome, the JGI has also continued to …
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Fishing for Novel Cellulose Degraders
… genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is a boxful of lures. Designed with feathers or wires to mimic an insect … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
…   The Science Scientists have fully decoded the genome of an oil-producing green alga, and demonstrated precise … gene targeting in the genome in the November 2025 issue of The Plant Cell. Auxenochlorella is an allodiploid hybrid of two species, similar to a mule, but that is still able to …
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JGI@25: Strengthening Soybean
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … the potential of seed oils as biofuel. After analyzing the original sequence, Gary Stacey of the University of Missouri …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… A special issue of Synthetic Biology celebrates research enabled by the JGI … and synthesis work. This is where the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … more than 10 papers, including two Nature Plants publications, in five years, have come out of the …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring polar bears in winter scenes that came with crayons in various shades of white. To researchers searching for sequences of RNA viruses in large data sets, their work may be akin to …
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… As part of the JGI’s 25th anniversary celebration, the 2022 Annual … sequencing for the Human Genome Project out to the future of the institution. Their talks shed light on how the JGI … went on to explain that the JGI’s very first project — the revolutionary work of the human genome project, which spanned …
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A Collaboration to Improve Plant Genome Annotations Across Species
… which specializes in genome improvement for plants. As part of that partnership, the JGI and HudsonAlpha researchers led … out to characterize the transcriptome – the complete set of RNA molecules transcribed from all the genes within a … to improve plant genome annotations at the US Department of Energy (DOE) Joint Genome Institute (JGI)*, a national …
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