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DAP-seq Drives Robust Mapping of Gene Regulation
… broccoli and trees like poplar, spanning about 150 million years of evolution,” said Leo Baumgart, first author on the … Advancing gene regulation mapping Previous methods to identify where transcription factors (TFs) — the proteins that … that a binding site has been maintained through millions of years of evolution, suggesting it plays an important …
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Promoting the Power of Viral Metagenomics
… deep-sea hydrothermal vents – and computationally identifying which sequences represent viruses that were present in …
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Ian Blaby
… in cyanobacteria Nature Communications 15(1) 3167. 2024 Simirenko et al ., gRNA-SeqRET: a universal tool for … Biology JGI Co-chair, People Stewardship committee (2020-2022) UCLA Molecular Biology Institute Postdoctoral Award …
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The Megadata of Lake Mendota - Part 1: Many, Many Mers
… lab has been sampling the microbes of that lake for over 20 years, to understand how the freshwater ecosystem works.  So a few years ago, when they set out to analyze 500 metagenomes, it …
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Computationally Classifying Fungal Lifestyles
… methods were applied on sequenced fungal genomes to classify gene families. The Science As a proof of concept, … an algorithm that “taught” a computer how to classify 101 representative genomes of Dothideomycetes, the … of fungi, by lifestyles. The machine “learned” to identify data generated in part through the 1000 Fungal Genomes …
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Emiley Eloe-Fadrosh
… from host-associated and environmental samples to identify and characterize genomic information from uncultivated …
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Cataloging the Microbes that Manage the Health of River Systems
… of river health diagnostic systems to monitor for and identify land use or water quality changes. Summary Rivers are key … support by US National Science Foundation awards DEB1840243, EAR1836768 and DEB1457794. Funding support also was …
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JGIota: A Surprise for Chloroflexota — The First Flagella!
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… they sequenced DNA ‘marker’ gene sequences to identify the microbes. And in order to determine what genes the …
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Alabama A&M Interns Access An Abundance of Knowledge
… In 2024, the DOE Joint Genome Institute and Alabama A&M …
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A Mentor’s Perspective on Training the Next Generation
… Over the years, hundreds of interns have come to the JGI from all …
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Learning to Look
… databases. In this case, the machine “learned” to identify a certain type of bacterial viruses or phages called … 70,000 microbial and metagenome datasets, ultimately identifying more than 10,000 inovirus-like sequences compared to … in 3,609 (6 percent) of the 56,868 microbial genomes and 2,249 of the 6,412 (35 percent) metagenomes mined for this …
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