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Integrating Experimentation with Data
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From Competition to Cooperation
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UC Merced Interns Reflect on Their JGI Summer Projects
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Doubling Down on Known Protein Families
… a dark room with a flashlight, only able to clearly identify what falls within that single beam. When it comes to … but we knew the families,” Kyrpides said. Yet, “almost 20 years of metagenomic data and metagenomic analysis, and … of new protein families had started to plateau in recent years, perhaps suggesting that scientists had “captured” …
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Access to Rock Star Scientists
… done the groundbreaking work you’ve been reading about for years! And you can ask them about it! And they’re super …
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DAP-seq Drives Robust Mapping of Gene Regulation
… broccoli and trees like poplar, spanning about 150 million years of evolution,” said Leo Baumgart, first author on the … Advancing gene regulation mapping Previous methods to identify where transcription factors (TFs) — the proteins that … that a binding site has been maintained through millions of years of evolution, suggesting it plays an important …
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Promoting the Power of Viral Metagenomics
… deep-sea hydrothermal vents – and computationally identifying which sequences represent viruses that were present in …
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… rapid environmental changes. Researchers were able to identify specific genes that allow the algae to adapt to sudden … more nutrients to fuel growth. The Impact Over the last 40 years, summer sea ice in the Arctic has decreased by more …
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Ian Blaby
… Biology JGI Co-chair, People Stewardship committee (2020-2022) UCLA Molecular Biology Institute Postdoctoral Award …
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The Megadata of Lake Mendota - Part 1: Many, Many Mers
… lab has been sampling the microbes of that lake for over 20 years, to understand how the freshwater ecosystem works.  So a few years ago, when they set out to analyze 500 metagenomes, it …
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Computationally Classifying Fungal Lifestyles
… methods were applied on sequenced fungal genomes to classify gene families. The Science As a proof of concept, … an algorithm that “taught” a computer how to classify 101 representative genomes of Dothideomycetes, the … of fungi, by lifestyles. The machine “learned” to identify data generated in part through the 1000 Fungal Genomes …
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Emiley Eloe-Fadrosh
… from host-associated and environmental samples to identify and characterize genomic information from uncultivated … Nat Microbiol . 8(5):751-753. Nayfach A, et al. 2021. A genomic catalogue of Earth’s microbiomes. Biotechnol . …
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