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A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … The Science CRISPR-Cas9 is a powerful, high-throughput gene-editing tool that can help scientists engineer … these sgRNAs, cloning them alongside CRISPR-Cas9 into an expression vector to create an sgRNA plasmid library. The …

A special issue of Synthetic Biology celebrates research enabled by the JGI … Fashioning DNA outside a cell is key to interrogating what genes do, how they work, and applying them to environmental … in the Synthetic Biology special issue, Modular cell-free expression plasmids to accelerate biological design in cells …

… synthesis, and metabolomics at the JGI for projects of relevance to Department of Energy (DOE)  Mission Areas . Through this program, the … the completion of a project, the JGI makes the assemblies, gene annotations, and analyses available to the community at …

The Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new …