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… Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that enable …

… This single environmental trigger highlights efficiency for users … salt triggers this metabolic shift, the team combined RNA sequencing across multiple time points with Cappable-seq, a … begins on the genome. This revealed a sweeping cellular response: The bacterium absorbs potassium ions to …

… The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire … 2012, with a focus on addressing critical energy and environmental challenges. Through innovative research in … project. These advancements contribute to the development of new biofuels and sustainable biochemicals. The DNA …

… In order to do so, these organisms share space at cellular scale: fungi stretch a network of tendrils called … to study both sides of this interaction up close, using RNA sequencing to understand gene expression: one of the first … with Cole and Serrano to collect and analyze the single nuclei and spatial transcriptomics data this work …

… 21-23, 2023, attendees joined the JGI Annual Genomics of Energy & Environment Meeting.  A wide array of invited speakers shared how research infrastructure – DNA sequencing, synthesis, metabolomics, data analysis, and new … that completely depends on the context and oftentimes a single molecule can be what I like to call …

… See below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, … to soil carbon storage during simulated range shifts of plant-fungal symbionts … Elucidation of the gene regulatory networks governing terpenoid-mediated plant environment interactions to enable advanced bioenergy crops …

… A “bait and hook” single-cell genomic approach to bioprospecting. The Science One of … pools, followed by whole genome amplification and shotgun sequencing. The team first tested the approach on bacterial … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …