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An Enzyme System to Help Catalyze Bioproduction of Plastic
… By characterizing the structure and function of a methylthio-alkane … enzyme, Methylthio-alkane Reductase (MAR) in host bacteria Rhodospirillum rubrum . Their work in Nature Catalysis … done the synthesis, metagenome mining, all the way from sequencing to functional characterization, and a project …
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Tracking the Origins of Methane-Producing Microbes
… Mini-Metagenomics Approach Helps Identify Novel Archaeal Methane Metabolism. Methane-producing archaea are estimated to produce 500 million tons of … the microbes into small pools of cells that were then sequenced separately. From these samples, 111 … and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that enable …
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Calculating the Costs of Multiple Switchgrass Gene Copies
… led by researchers at the University of Texas (UT) at Austin, the HudsonAlpha Institute for Biotechnology … with many commonly cultivated commercial crops such as wheat, peanut, oat, banana, potato, etc., switchgrass is … , which can have pronounced ecological and evolutionary consequences. A previous study conducted by our research team …
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Building Wet and Dry Lab Skills
… the second year of Alabama A&M University students coming to the DOE Joint Genome Institute for research and training experience funded by a …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… with the prospect of meta-analyses boosted by AI and Machine Learning — JGI researchers and collaborators work to … catalyzed by microbial communities. By pairing RNA or DNA sequencing with tracings of stable, heavy isotopes, SIP … a  Minimum Information for any Stable Isotope Probing Sequence (MISIP) . They differentiate between required …
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10 From JGI on the 2019 Highly Cited Researchers List
… their 2019 list of Highly Cited Researchers , which includes 10 affiliated with the JGI . The 2019 list focused on Highly Cited Papers, defined in the Methodology section as “those that rank in the … Nature Genetics, the work is part of a long-term project to sequence, annotate and analyze the genomes of more than 300 …
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Gut Fungi: Unexpected Source of Novel Chemicals
… Fungi from herbivore poop make surprisingly complex compounds — an energetically expensive feat … too costly for them. The Science Anaerobic fungi, which die in the presence of oxygen, dwell in herbivore guts and help … finnis . In work reported in 2017, the fungal genomes were sequenced by the U.S. Department of Energy (DOE) Joint …
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Tanja Woyke Elected to American Academy of Microbiology
… of Microbiology (AAM) ! She is among the 68 new Fellows in the Class of 2020, selected from 118 nominees. The selection process for AAM Fellows is based on … One example, published in Nature , applied single-cell sequencing to decode genomes of bacteria and archaea from …
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JGIota: A Biofuel Breakthrough in Anaerobic Fungi with Michelle O'Malley and Tom Lankiewicz
… of UC Santa Barbara discuss the importance of studying anaerobic fungi, as well as a recent discovery that …
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Game On: High School Students Drive Everglades Metagenomics Study
… In late June, Kathleen Lail, a member of JGI’s Sample … DNeasy PowerSoil Kits and sent the samples to the JGI for sequencing.  While JGI processed, sequenced, and analyzed the soil samples, the JGI offered 7 … and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that enable …
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Training the Next Generation of Talent
… New Graduate Internship Program Builds Bridges Between DOE JGI, UC Merced … Johnson in Wang’s group on developing an algorithm for RNA-Seq assembly. RNA-Seq is a technique for profiling the small fraction of a …
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JGIota: A Surprise for Chloroflexota — The First Flagella!
… Marike Palmer and Brian Hedlund study organisms living in hot springs. Hear how their recent work revealed more about the …
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