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Graduate Students Get Thesis Research Opportunity at the JGI
… selected to carry out part of their thesis research at 12 host national laboratories or facilities between 3-12 … are developing cutting edge technologies to answer our most pressing problems. I’m very much looking forward to … the United States, and is working to address some of the most pressing challenges of our time. For more information, …
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A Complex Confection Decoded: Sugarcane Reference Genome
… biotechnology. The Science Considered the world’s most harvested crop by tonnage, sugarcane accounts for 80% of … for 80% of sugar production worldwide, but has one of the most complex genetic blueprints. Assembling a genome has been …
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Doubling Down on Known Protein Families
… but we knew the families,” Kyrpides said. Yet, “almost 20 years of metagenomic data and metagenomic analysis, … enzymes.” Leveraging Protein Families in a New Way The discovery of new protein families had started to plateau in … explained. “Replicating that 100 times would have been almost impossible.”  When the team was finished with this …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… the viruses repeatedly attempted to infect and destroy the host archaea – and how the  microbes resist. The battle waged … lyse the microbial cells. This demonstration of the virus-host arms race in uncultivated yet abundant subsurface … are using Altiarchaea as a model system to study virus-host interactions. Approximately 150 archaeal viruses had …
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Simon Roux
… of new experimental approaches to link viruses to their host(s), collaboration with JGI users for analyzing viral … foundational knowledge of viral diversity and virus-host interactions in microbial systems. Through a 2021 DOE … explore the ecological and evolutionary drivers of virus-host dynamics in soil microbial communities. …
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Webinar: PhycoCosm Tutorial
… agree, we also have a way to do manual annotation – not covered in these tutorials 6.  Q: On the genome synteny page, … the United States, and is working to address some of the most pressing challenges of our time. For more information, …
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The Expanding Universe of Methane Metabolisms in Archaea
… propose a scenario where methanogenesis is possibly the most ancient energetic metabolism in the Archaea, and was lost many times independently during archaeal evolution or … short-chain alkane oxidation,” Borrel and Gribaldo said. “Overall, these results show a striking case of how metabolic …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… useful for understanding the microbiome of the earth, but most species do not grow easily in the lab. To access the … a method called Multiple Displacement Amplification, and most genomes that were acquired through it were usually only … is desirable in the microbiome field due to its high recovery of single-cell genomes. This is key to better …
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Tracing the Evolution of Shiitake Mushrooms
… originated in the tropics of the Asia-Australia region. Overall, pangenome analysis showed significantly more …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… a potent greenhouse gas, regulate Earth’s climate. Most methane is produced in environments without oxygen … . These ancient, single-celled organisms thrive in most  environments devoid of oxygen and until recently were … and, if so, to what extent.  “These new groups were discovered not by cultivation, like the original methanogens …
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A Sorghum Pangenome Opens More Doors to Discovery
… Plants , on the short list of plant genomes deemed most important to DOE mission and plant science. The work … relevant to national energy priorities. More than a discovery in itself, this pangenome is a tool. It shows genetic … the switch away from shattering. “That was one of the most exciting things for me as a computational biologist. …
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Extracting the Secrets of Secondary Metabolites
… a demonstration, the researchers used CRAGE-CRISPR for discovering active secondary metabolites and helping them … CRAGE, researchers are no longer limited to using model host microbes; theoretically, any microbe can serve as the … Lab) can then employ CRISPR in a variety of microbial hosts. Summary Photorhabdus luminescens proves fatal to …
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