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… The practices that support agriculture – such as efficiently using dwindling water resources and restoring and maintaining healthy soils – are at the heart of … User Facility  located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE …

… Science Program. Fashioning DNA outside a cell is key to interrogating what genes do, how they work, and applying … more than 10 papers, including two Nature Plants publications, in five years, have come out of the … Transcriptional control of  Clostridium autoethanogenum  using CRISPRi ). Now, they’ll be able to further explore how …

… CRAGE-CRISPR combo helps further demystify biosynthetic gene … for growth yet essential for survival, may now be easier to characterize following a proof-of-concept study in which … By employing CRAGE, researchers are no longer limited to using model host microbes; theoretically, any microbe can …

… Cas14 proteins discovered from JGI’s IMG/M database and biochemically … Microbial Genomes and Microbiomes (IMG/M) suite of tools managed by the U.S. Department of Energy (DOE) Joint … of a new family of Cas proteins, named Cas14. Using these sequences as a starting point, JGI data …

… A new approach for improving functional annotation in fungal … yeast Saccharomyces cerevisiae , allowing this species to grow better than its closest relative S. paradoxus at … a way to map associations between genotype and phenotype using a strategy called reciprocal hemizygosity analysis via …

… A new view into a symbiosis could offer benefits to address … been able to study both sides of this interaction up close, using RNA sequencing to understand gene expression: one of … at gene expression in both plant cells and fungal cells. Using a technique called single nuclei RNA sequencing, the …

…   Visualizing a novel, candidate viral genome found in the deep subsurface … researchers described how the viruses repeatedly attempted to infect and destroy the host archaea – and how the  … populations respond to virus infections, researchers are using Altiarchaea as a model system to study virus-host …

… A fungus relies on bacteria to regulate key components of its … control over reproduction was a likely key to this evolutionary transition. Using this model, researchers also generated the first … This research was supported by the National Science Foundation and …

… By characterizing the structure and function of a methylthio-alkane … reductase system, researchers could open avenues for using bacteria to produce ethylene and more.  Microbes excel at recycling … User Facility located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE …

…   Our Sequencing Technologies Group is well-integrated across JGI departments to ensure a robust offering of sequencing capabilities and products to our users. This includes scaling the technologies and … An assay used for profiling transcription factor binding sites across entire genomes. This technology has …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number … that showcase our collaborations and capabilities to enable great science that will help solve energy and … inhibit microbial methane production. Another effort is in using microbial understanding to formulate a vaccine for …

… Panicum hallii genomes offer insights to drought tolerance. The Science … model to study drought tolerance in perennial grasses using Panicum hallii (Hall’s panicgrass), by generating two … The work conducted by the US Department of Energy Joint Genome Institute, a …