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Doubling Down on Known Protein Families
Using a novel computational approach, researchers confirm microbial diversity is wilder than ever. Imagine researchers exploring a dark room with a … but we have also pushed the boundaries by applying AI methodologies to unravel their roles,” Pavlopoulos said. …
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Comparative Genomics Using the Integrated Microbial Genomes and Microbiomes (IMG/M) System: A Deinococcus Use Case
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Draft Genome Assemblies of Ionic Liquid-Resistant Yarrowia lipolytica PO1f and Its Superior Evolved Strain, YlCW001
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2024 Progress Report
… facility, we provide advanced genomic capabilities, large-scale data, and professional expertise to support the global … processed 13,700 metabolomics samples With our users, 247 publications were published   … Our primary objective is to … more than doubled the number of known protein families by using AI clustering algorithms to identify billions of …
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Using BLAST to Teach “E-value-tionary” Concepts
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A Guide to Gene‐Centric Analysis Using TreeSAPP
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Katherine Louie
… capabilities and product offerings for JGI users.  Using cutting-edge mass spectrometry-based techniques, the … drive patterns in rhizosphere microbial community assembly. Nat Microbiol. 2018;3: 470–480. 7. Louie KB, Bowen … Sci Rep. 2013;3: 1656. … Education … Selected Publications …
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Calculating the Costs of Multiple Switchgrass Gene Copies
Scientists have discovered that the candidate bioenergy feedstock switchgrass has adapted to … led by researchers at the University of Texas (UT) at Austin, the HudsonAlpha Institute for Biotechnology … alters genomic diversity, fitness, and adaptability. Using a combination of genomic, quantitative genetic, …
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Enlarging Windows into Understanding Gene Functions
… affect traits. In a text file, the rows of letters A, T, C and G appearing over and over in a dizzying array of … capability; no one else can do it in the world at this scale.” A bottleneck in the DAP-seq protocol, however, is … TFs and regulatory networks are conserved across fungi.” Using multiDAP-seq, Nagy’s team is comparing five fungal …
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Tracing the Evolution of Shiitake Mushrooms
New genomes highlight the diversity of white rot fungi in the genus Lentinula   The Science Shiitake mushrooms get … they often source their nutrients — the shii tree, a Japanese relative of the oak. These fungi are part of the … 60 existing sequences, this work expands the family tree for Lentinula. Within those samples, this study also tracks …
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Gut Fungi: Unexpected Source of Novel Chemicals
Fungi from herbivore poop make surprisingly complex compounds — an energetically expensive feat thought to be too costly for … source of antibiotics. Indeed, these anaerobic fungi may be using these compounds for self-defense. But the compounds …
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Interdisciplinary delegation from the University of Duisburg-Essen explores collaborative opportunities with Lawrence Berkeley National Laboratory
A two-day kick-off meeting held at Lawrence Berkeley National Laboratory (Berkeley Lab) marked the visit of an esteemed interdisciplinary delegation from the University … to small individual workshops. Of common interest is the method development to study active sites or single cells in …
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