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… about natural products and the science and scientists of secondary metabolism. Natural products, secondary … research, “Natural Prodcast” serves as an important line of communication to the scientific community. Host Dan … and future developments, and how the JGI can be part of that space.   …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … to provide colleagues at the Salk Institute with genomic DNA samples from Ruminococcus flavefaciens (XPD3002). With …

… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the … sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized these sgRNAs, cloning …

… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most species do not grow easily in the … years, extracting single cells and then amplifying their DNA for genome sequencing was no easy task. The traditional …

… Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short … associated proteins that can target single-stranded DNA (ssDNA). The discovery was made possible by mining the … Institute. The Impact The ability to accurately edit genomes (that is, repair gene mutations, and …

… Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant … in  Microbiome , researchers from the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science facility, have increased the number of …

… hydroxyapatite, a high-value biomaterial with a wide range of industrial applications. The team was led by researchers at two U.S. Department of Energy national user facilities – the DOE Joint Genome … in the development and biotechnology applications of various biomaterials. These efforts align with BER …

… Survey of Setaria's natural diversity reveals seed dispersal in … Center (Danforth Center) drove up and down the highways of the continental United States, occasionally pulling over to the side of the road to collect small weedy plants and bring them … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …

… data set will help identify how different elements of the ecosystem interact and respond to changes in the … their genetic diversity. They hold economic value as both biofuel feedstock and their role in carbon sequestration. … metagenomics, scientists were able to analyze the DNA of microbes living around the tree roots in the …

… In a special issue of mSystems , out May 14, 2019, JGI researchers are among the authors who offer perspectives on what the next five years of innovation … in soil for the first time. A second approach known as DNA stable isotope probing (DNA SIP) relies on incubating …

… A quick snippet on Antonio Camargo and Simon Roux, a few of the JGI researchers behind software that finds plasmids and viruses within microbial … As mobile genetic elements like viruses spread their DNA, they can affect how microbes cycle nutrients and adapt …

… wants to understand how viruses impact the release of greenhouse gases from Arctic permafrost. But to see what they’re doing, he first needs their DNA.   …