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Natural Prodcast Episode 6: Marc Chevrette
… DAN: You’re listening to the US. .Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … metabolomics, and natural products in plants, fungi, and microorganisms. If you want to collaborate, let … Prodcast, our conversation with Marc Chevrette, a postdoctoral researcher from the laboratory of Jo Handelsman at the …
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Taking Stock of the Known and Unknown Microbial Space
… decades, advancements in sequencing technologies have led to an abundance of microbial genomes becoming available to the global … experimental validation.  Microbes run the world, playing key roles in regulating global nutrient cycles. The … User Facility located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE …
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An Enzyme System to Help Catalyze Bioproduction of Plastic
… By characterizing the structure and function of a methylthio-alkane reductase system, researchers could open avenues for using bacteria to produce ethylene and more.  Microbes excel at recycling … with nitrogenase M-clusters, whose precise identity is of key interest. With this understanding, future work can focus …
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JGI@25: Roots of a Mutualist Relationship
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … that showcase our collaborations and capabilities to enable great science that will help solve energy and …       Francis Martin on the main impact of ectomycorrhizal fungi, excerpted from his talk at the 2015 JGI Annual …
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The Expanding Universe of Methane Metabolisms in Archaea
… Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key role in determining the composition of the Earth’s …
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Boosting Small Molecule Production in Super “Soup”
… still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both the machinery to … this collaboration is that we’re doing work in yeast, a key platform organism that has been used historically for … User Facility  located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE …
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JGI@25: Using Team Science to Build Communities Around Data
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … that showcase our collaborations and capabilities to enable great science that will help solve energy and … 1000 fungal genomes to create two reference genomes for all fungi families — essentially, the foundation for an …
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Products
… Mass spectrometry based metabolomics Below is a table of standard product offerings, including a description of … as well as target cycle times from sample receipt to completion of standard analysis.  Raw data is provided … below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the standard analysis is complete. Raw …
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Learning to Look
… learning approach significantly expands inovirus diversity. To answer the question, “Where’s Waldo?” readers need to look for a number of distinguishing features. Several characters may be … with more than 3,400 different proteins, many linked to key functions such as virion structure and extrusion, and …
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Boosting Small Molecule Production in Super “Soup”
… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical output due … this collaboration is that we’re doing work in yeast, a key platform organism that has been used historically for … User Facility  located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE …
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Picking Up Threads of Cotton Genomics
… Analysis reveals cotton genome stability across global lineages . Come harvest … goal has been for all this new cotton work, and even the original cotton project was to try to bring in molecular … among five allotetraploid cottons, along with noted key fiber development genes. The results indicate remarkably …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in … With metagenomic sequencing, researchers have found more of these viruses than ever before, in all kinds of … for human microbiome data. In other environments, such as terrestrial soil, having additional isolates and metagenomic …
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