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Applying Viral Genomics Expertise to Understanding the Human Virome
JGI researchers lend expertise to develop tools and data hub for NIH program. While the microbes in, … host microbes impact the regulation of global nutrient cycles. The JGI’s latest strategic plan (download a copy  …
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JGI Early Career Researchers Featured in mSystems Special Issue
… head Emiley Eloe-Fadrosh outline more targeted approaches to reconstruct individual microbes in an environmental … approach uses fluorescence-activated cell sorting (FACS) to sort cells into several small pools before sequencing to … While microbes regulate the planet’s biogeochemical cycles, viruses infecting microbes shape global ecological …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in … cultivation can’t. The Science At first, viruses are merely toolkits. To do anything, they must find a host, and not … the roles viruses and their host microbes play in nutrient cycles. … This work was supported by the U.S. Department of …
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Fishing for Novel Cellulose Degraders
A “bait and hook” single-cell genomic approach to bioprospecting. The Science One of the most vital pieces … is a boxful of lures. Designed with feathers or wires to mimic an insect or a particular movement, each of these … known to be key contributors to the planet’s biogeochemical cycles, but the vast majority remains uncultivated and …
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
… wild populations for the first time. For years, Elizabeth (Toby) Kellogg and other researchers at the Danforth Plant … of the continental United States, occasionally pulling over to the side of the road to collect small weedy plants and … (Setaria viridis), a small model grass with a short lifecycle that uses a carbon fixation process known as the C4 …
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Three Join the JGI User Executive Committee
… month – Sneha Couvilion of Pacific Northwest National Laboratory, Chris Schadt of Oak Ridge National Laboratory and Elizabeth “Lizzy” Wilbanks of the University of … He’s interested in how microbes influence biogeochemical cycles in soils and sediments and plant-microbial …
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How to Target a Microbial Needle within a Community Haystack
Microbiology has developed, tested and deployed a pipeline to first target cells from communities of uncultivated … of microbes that play key roles in global biogeochemical cycles remains unexplored and uncultivated. Developing a more targeted genomic approach would allow researchers to focus on specific microbes within metagenome samples and …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
… that showcase our collaborations and capabilities to enable great science that will help solve energy and … viruses impact many ecological processes, including carbon cycles. “Whether or not you planned it, viruses are most … Simon Roux , the Viral Genomics Group Lead at the JGI.  To understand the microbiome systems underpinning a broad …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel … User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab), to fill in these gaps of knowledge. In … actinobacteria play roles in both the carbon and nitrogen cycles, break down plant mass (think biofuels ), enhance …
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Taking Stock of the Known and Unknown Microbial Space
… decades, advancements in sequencing technologies have led to an abundance of microbial genomes becoming available to the global research community.  Published January 17, … the world, playing key roles in regulating global nutrient cycles. The information gained from understanding the …
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The Power of One, Amplified
… showed that single cell genomics can add significant value to the other commonly used culture-independent sequencing … (MAGs), and that dominant populations varied with respect to the amount of within species recombination, indicating … Impact Though microbes help regulate the planet’s nutrient cycles and are potentially of use in fields ranging from …
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The More the Merrier: Making the Case for Plant Pan-genomes
… abide by the concept, “the more the merrier,” with respect to their genomes. In their base state, they are diploids … lose many genes after such events, returning their genomes to a diploid state while retaining multiple copies of some … three  Brachypodium  grasses have small genomes, short life cycles and can be easily transformed, traits that make them …
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