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A Plant Root Atlas for Tracking Developmental Trajectories
… type and cell identity mutants . Dev Cell. 2022 Feb 28. S1534-5807(22)00033-8.doi: 10.1016/j.devcel.2022.01.008 Relevant … Five Berkeley Lab Scientists Receive Prestigious Five-Year Research Grant   … The U.S. Department of Energy Joint …
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Pinning Down a Piece of Photosynthesis
… light, transport molecules and regulate reactions. Identifying these proteins and then figuring out what they are … set out to tackle some of these genes, expressing and purifying the range of proteins these genes produced, to … a similar region —  a domain of unknown function, DUF2470. In the world of proteins, a domain of unknown function …
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Olpidium, The Key to the Origin of Terrestrial Fungi
Olpidium zoospores remained largely untouched until seven years later. In 2018, as members of the ZyGoLife consortium … to the sequencing effort by the JGI and ZyGoLife in recent years. With the much more extensive taxonomic and genetic … diversification events occurred approximately 650 million years ago, and that the first terrestrial fungi predate the …
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The More the Merrier: Making the Case for Plant Pan-genomes
… more than once, and these events took place a million years apart: the individual with a maternal  B. distachyon parent (D plastotype) some 1.4 million years ago (Mya), while the S plastotype was a more recent …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… in Complex Systems (LRC) in Menlo Park, Calif. In the June 24, 2022, issue of the journal Science, Volland and … conducted some microscopy studies over the next couple of years, and realized it was a sulfur-oxidizing prokaryote. … the study, performed the 16S rRNA gene sequencing to identify and classify the prokaryote. “I thought they were …
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I-Min (Amy) Chen
A, Chu K, Ritter SJ, Reddy TBK, Mukherjee S et al. IMG/VR v4: an expanded database of uncultured virus genomes within a … annotations and metadata. Nucleic acids research Jan 2024 Chen IA, Markowitz V, Szeto E, Palaniappan K, and Chu K. … Data Analysis System in an Academic Setting, SSDBM 14, July 2014 … Selected Publications …
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Extracting the Secrets of Secondary Metabolites
CRAGE-CRISPR combo helps further demystify biosynthetic gene clusters.  The Science Microbial … active secondary metabolites and helping them identify and describe the functions of the biosynthetic gene … highly regulated in bacteria, making it difficult to identify which pathway corresponds to which metabolite. Finding a …
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The Power of One, Amplified
… in, on, and around the planet remain unknown. In recent years, advances in sequencing technologies and bioinformatic … diverse than those within more moderate ecosystems. A few years ago, a candidate bacterial lineage was identified from … This work was also sponsored by NSF grants DEB-1441717, OCE-1335810, and OIA-1826734 to RS. …
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Help from Citrus’ Bitter, Hardier Cousin
… to 2016, in Florida alone this disease caused an estimated $4 billion in losses. Currently, ninety percent of Florida … JGI’s Daniel Rokhsar, published over the last half-dozen years, on the ancestral origins of  Citrus sinensis , the …
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Waiting to Respire
… ancestral bacteria’s energy sources. More than two billion years ago, cyanobacteria acquired the ability to produce …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… rely on enzymes that have been evolving for billions of years. However, these enzymes are often loosely understood, … plant, fungi and animal. This analysis led them to identify 2,938 putative AT  genes. Within the AT genes identified … that even enzymes that evolved separately for billions of years have some common signatures of muli-substrate …
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The Expanding Universe of Methane Metabolisms in Archaea
… gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key … metabolisms is “vastly underestimated.” In the March 4, 2019, issue of Nature Microbiology , they mined the … with the first traces possibly at ~3.5 Gy (billion years),” Borrel and Gribaldo said in an email. “Therefore, …
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