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2022 Progress Report
DOE Joint Genome Institute (JGI). Researchers from the DOE Systems Biology Knowledgebase (KBase), the National Microbiome Data Collaborative (NMDC), and Berkeley Lab Biosciences Area …
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From Intern to Published Scientist: The Journey of a JGI-UC Merced Intern
… ecosystem,” said Salamov, one of Wint’s mentors and a data scientist at the JGI. Previous studies were conducted … predictor of gene expression levels using machine learning tools. “This was very exciting to see how Rhondene not only … the research question and applied it to such a large data set, but also went all the way through to convert her …
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Evolution of a multi‐step phosphorelay signal transduction system in Ensifer: recruitment of the sigma factor RpoN and a novel enhancer‐binding protein triggers acid‐activated gene expression
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
Across four forests, researchers have leveraged data from the 1000 Fungal Genomes project to form new … to support a forest, and species vary across Earth’s ecosystems.  Recently, in work  published in  New Phytologist , … RNA to understand gene expression, and developed new tools to map that soil RNA to fungal genomes.  The U.S. …
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Learning to Look
… a similar type of search in microbial and metagenomic databases. In this case, the machine “learned” to identify a … co-infecting phages and with the host’s CRISPR-Cas immunity systems. Countering Co-Infections, Ensuring Host Survival … of phage-bacterial coevolution and are also useful tools in CRISPR-Cas applications, but we are limited in our …
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Triggering Morel Fruiting
… because they influence geochemical cycling in forest ecosystems. By deciphering the fruiting-related decomposition … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  … . … Morel Mushrooms on MycoCosm Data Portal …
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Mateus Fiamenghi
… and analysis of Mobile Genetic Elements from Metagenomic Data.  Mateus’s GitHub …
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Duplications and losses of genes encoding known elements of the stress defence system of the Aspergilli contribute to the evolution of these filamentous fungi but do not directly influence their environmental stress tolerance
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… that can’t be cultured by analyzing and then extrapolating data obtained from environmental samples — to identify over … and … that was really the foundation for many of the tools that are available these days and that are widely used … actually tested in the 2011 paper. In 2015, the study’s dataset became material for a hands-on undergraduate …
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The More the Merrier: Making the Case for Plant Pan-genomes
… quality genome assemblies for all three grasses. With these datasets, researchers made a pan-genome containing four  B. … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  … . … Brachypodium distachyon on Phytozome Data Portal …
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Antonio Camargo
… classification of Mobile Genetic Elements from metagenomic data.  Antonio's GitHub …
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A Natural Mechanism Can Turbocharge Viral Evolution
… has looked for DGRs in a broad range of publicly available datasets. They’ve discovered that DGRs are not only … level. Scientists might then harness them as molecular tools for research and industry applications. Summary In … and through a Challenge Grant from the California NanoSystems Institute at the University of California Santa …
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