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Zhong Wang
Research in the Analysis R&D group focuses on developing new bioinformatics solutions to support … and external scientists, the Wang group has developed customized data analyses and software to enable “grand-scale” scientific projects. These solutions include large-scale genome …
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Synthesis
The team has three subgroups: Synthetic Biology Lab : a user science group dedicated to user project design, assembly, and quality control Strain … Engineering Group : a research & development group and focused on new technologies and optimizing tools — including …
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JGI Earth Month: Healthy Streams, Nutritious Microbes?
In April 2020, we mark both the 50th celebration of Earth Day on … the world’s rivers and their microbial communities. He’s focusing on the Arkansas River and how microbes might be influencing its health.  He sat down with me to talk about his project, and riffed a bit on what it means in a …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but … To access the genomes of uncultured  microbes , scientists usually employ two different methods; shotgun metagenomic … like plasmids, the picture is far from complete.  In 2021 , scientists at St. Jude Children’s Research Hospital …
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A One-Stop Shop for Analyzing Algal Genomes
… an interactive browser that allows algal scientists and enthusiasts to look deep into more than 100 algal genomes, … genetic underpinnings responsible for these traits takes us closer to harnessing algae for bioenergy and the greater … Office of Science of the U.S. Department of Energy [DE-AC02-05CH11231]. S.C., B.K., and I.V.G. were supported in part …
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Len Pennacchio
In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused on applying state-of-the-art molecular methods to … in Genome Biology & Technology (AGBT)” … Education … About the Deputy of Genomic Technologies … Selected …
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Fishing for Novel Cellulose Degraders
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … and unknown. The challenge remains to learn more about what microbes are present in any given … spectrometry-based enzyme activity assay. The work was  reported in  The ISME Journal . While the screen caught …
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Marcel Huntemann
… exchange and assists with large scale computations on R&D projects. …
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DOE JGI Interns Share Their Summer Experiences
… part of the DOE JGI’s efforts to promote diversity and inclusion in the sciences, among the interns were two … groups, respectively. Each of the interns spoke briefly about their time at the JGI at … with T.B.K. Reddy on the Genomes OnLine Database; Sarah Fruchart , who worked with Matt Blow; Sean Bray , who also …
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A Complex Confection Decoded: Sugarcane Reference Genome
… the location of genes that provide resistance to the brown rust disease that can devastate a crop. The Impact In … for the sugarcane cultivar R570 has been generated and  reported in the journal  Nature . The work led by … partly enabled by the JGI’s Community Science Program; in 2018, a monoploid reference sequence of sugarcane …
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Better Genome Editing for Bioenergy
… of the genes in a lipid-prolific yeast. The Impact The team used this set of guide RNAs on  Yarrowia lipolytica to … furthers the U.S. Department of Energy’s goal of producing sustainable fuels from alternative sources. Moreover, the … CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, but these …
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Tracing the Evolution of Shiitake Mushrooms
… highlight the diversity of white rot fungi in the genus Lentinula   The Science Shiitake mushrooms get their name from the same place they often … from around the world. By complete sequencing of 24 new mushroom genomes, and assembling genomes from 60 …
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