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Green Algae Reveal One mRNA Encodes Many Proteins
… messenger RNA, which encodes a single protein. Recently reported in the Proceedings of the National Academy of Sciences , a team of researchers has found numerous examples of polycistronic expression – in which two or … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Berkeley Lab and the Environmental …
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Dispatches From JGI Interns
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I-Min (Amy) Chen
… her Ph.D. in Computer Science. Her research has been focused on semantic and object-oriented data modeling, and … S et al. IMG/VR v4: an expanded database of uncultured virus genomes within a framework of extensive functional, … Data Analysis System in an Academic Setting, SSDBM 14, July 2014 … Selected Publications …
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Better Genome Editing for Bioenergy
… of the genes in a lipid-prolific yeast. The Impact The team used this set of guide RNAs on  Yarrowia lipolytica to … furthers the U.S. Department of Energy’s goal of producing sustainable fuels from alternative sources. Moreover, the team says the approach they used to validate their set of guide RNAs could be applied to …
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Gut Fungi: Unexpected Source of Novel Chemicals
… off early from aerobic fungi, which can breathe oxygen — just like we do. Oxygen is a rich source of energy, and because anaerobic fungi can’t harness it, scientists long held … Neocallimastix californiae , and Piromyces finnis . In work reported in 2017, the fungal genomes were sequenced by the …
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JGI Pitches 2022 Visiting Faculty Program Collaborations
… are solicited annually for the summer term (May through August) and selected projects will receive stipend and travel …
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A One-Stop Shop for Analyzing Algal Genomes
… an interactive browser that allows algal scientists and enthusiasts to look deep into more than 100 algal genomes, … genetic underpinnings responsible for these traits takes us closer to harnessing algae for bioenergy and the greater … genomic data on algae into one place, PhycoCosm allows users to easily compile data that answers what genes are …
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A Social Science Experience
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JGI@25: Following Fungi that Pry Apart Plant Polymers
… that will help solve energy and environmental challenges.   Usually, plants have the upper hand against any kind of … of years evolving tactics against potential threats. “Because plants can’t run away, they’ve evolved these really … that would be produced by microorganisms — out,” said JGI user/collaborator Michelle O’Malley, a chemical and …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… is central to our ability to offer host-engineering for our users,” says JGI Director Nigel Mouncey. Using CRAGE, JGI has established a portfolio of microbial … individual genes, whole pathways, genome-editing tools, and reporters.” JGI-developed genetic engineering technique …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do anything, they must find a host, and not just any host will do. It must be a …
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JGI@25: Roots of a Mutualist Relationship
In March 2008, the genome sequence of the forest fungus Laccaria bicolor was published in the journal Nature . The mushroom has a symbiotic relationship with the poplar, a JGI … Having this first genome sequence of a mycorrhizal fungus shifted the focus from looking at single organisms to …
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