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User Support Analysis Group
… for diverse experiment types, with main focus areas being genome variation, transcriptomics and epigenomics. Our work varies in scope from the development of highly customized analysis workflows for new product types, to the development of automated analysis pipelines for standard sequencing …
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Alabama Agricultural & Mechanical University Internship Program
… 2024 was a year of firsts, including the flagship internship program between … Alabama Agricultural & Mechanical University and the Joint Genome Institute. AAMU students spent two months in … their mentors and fellow interns. Inspired by the success of the UC Merced internship program, they left the JGI more …
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Inspiring STEM Careers Through a Hands-on Everglades Microbiome Study
… Journal publication caps JGI pilot project with fledgling Florida … school scientists. The Florida Everglades evokes images of fanboats skimming over swamps, while alligators peer … cattails. In 2018, the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Expanding Virophage Diversity
… Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant … in  Microbiome , researchers from the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … analysis led to the identification of 328 “high quality” (based on completeness) diverse new virophage genomes …
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A Community Resource for Secondary Metabolite Researchers
… user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence … over 1.3 million publicly available bacterial and archaeal genome and contig sources.  The Impact Secondary metabolites …
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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … in Streptomyces coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions … assay. The second step consists of RNA sequencing of whole transcriptomes, and the third is determining the …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … most species do not grow easily in the lab. To access the genomes of uncultured  microbes , scientists usually employ … U.S. Department of Energy Joint Genome Institute (https:// ror.org/04xm1d337), a DOE Office …
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2022 Progress Report
… Pictured is a timelapse of the Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems … The vision of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user …
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Accelerating Metagenomics Discoveries with Deep Learning
… Metagenomic data, or DNA sequencing data gathered from whole samples rather than single cells or isolated strains, … insights from metagenomic data. In deep learning, a branch of machine learning, data is passed through algorithms … biologist at the US Department of Energy (DOE) Joint Genome Institute (JGI), presented on generating vector …
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A Redesign for Yeast’s Genome, Chromosome by Chromosome
… To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone … the goal is to create an entirely human-generated yeast genome. …
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Comparative transcriptomics of CAZy enzymes in white- and brown-rot agaricomycetes: Evolutionary insights into lignocellulose degradation and the relevance of GH16 glycoside hydrolase functional divergence
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Dan Rokhsar
… directed towards the sequencing, annotation, and analysis of three human chromosomes. After successful completion of the Human Genome Project, Professor Dr. Rokhsar ’s team has continued … by combining computational genome analysis, sequence-based genetic methods, and comparative developmental …
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