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… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … regular schedule for a while. Moving forward, I’m hoping to get a new one out every two weeks. This time, we’ve got a … of the Pfizer strain collection, and our collaborations to sequence that collection, mine genomes, and develop new …

… Tracing gene regulatory networks in the model fungus  Neurospora crassa . The Science A team … of California, Berkeley used a multi-omics approach to reconstruct and model gene regulatory pathways used by … Grant P01 GM-068087 “Functional Analysis of a Model Filamentous Fungus” and that are publicly available at the Fungal …

… Database has matured from six projects on a spreadsheet into a flagship  genomic metadata repository, making curated … manually curated metadata resources for organisms and environmental samples. The database aggregates relevant … a broad range of activities from proposal intake to publication. Information is also obtained and cross-checked …

… that showcase our collaborations and capabilities to enable great science that will help solve energy and environmental challenges. The 1KFG project represents … genomes that are both large and complex. The first publication of a genome generated by the OGG initiative — …

… Dr. Mouncey joined the DOE Joint Genome Institute in 2017 as the fourth Director in its 27-year history. He has a wealth of managerial … scientist at Roche Vitamins, Inc. in New Jersey and DSM Nutritional Products in Switzerland, and as Bioengineering … Secondary Metabolites Program head as well as our JGI Director. Click to learn more about the program's areas of focus, …

… Using a novel computational approach, researchers confirm … exploring a dark room with a flashlight, only able to clearly identify what falls within that single beam. When … these families. They divided the protein families up by environment and found only 7% of protein families were shared …

… Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse … presence of methanogens in nearly all types of anaerobic environments suggest the diversity of methane metabolisms is … of DOE missions related to clean energy generation and environmental characterization and cleanup. The JGI provides …

… Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both the machinery to … of DOE missions related to clean energy generation and environmental characterization and cleanup. The JGI provides …

… Innovative technology from this biomanufacturing … In  Nature Communications , researchers describe a strategy to recover high value products from human waste. They   … removing the organic matter before it re-enters the environment. Urine accounts for just 1% of wastewater, but it …

… Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical output due … of DOE missions related to clean energy generation and environmental characterization and cleanup. The JGI provides …

… with the prospect of meta-analyses boosted by AI and Machine Learning — JGI researchers and collaborators work to create FAIR datasets to maximize returns on … are active, and which microbes are eating what,  in the environment.  This distinction — between presence and …

… To provide broad plant genomic capabilities, the DOE Joint Genome Institute works in partnership with the … and involves more than 17 research groups. The team set out to characterize the transcriptome – the complete set of RNA …