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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… DNA outside a cell is key to interrogating what genes do, how they work, and applying them to environmental and energy … more than 10 papers, including two Nature Plants publications, in five years, have come out of the … in the organism Clostridium autoethanogenum. The microbe can utilize carbon oxides, including the greenhouse gas …
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Tracking the Origins of Methane-Producing Microbes
… , researchers at Stanford University, the Chan Zuckerberg Biohub, and the U.S. Department of Energy (DOE) Joint … to perform hydrogenotrophic methanogenesis and is not a member of the Euryarchaeota. The archaeum is a member of the … to these samples by sorting the microbes into small pools of cells that were then sequenced separately. …
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Accelerating Metagenomics Discoveries with Deep Learning
… difficult to assemble and interpret. The workshop aimed to showcase how researchers are utilizing deep learning to … machines to “learn” features. State of the art algorithms can perform astonishing degrees of feature recognition: for … magical; transform any length of amino acid sequence into a smaller, constant-length vector using deep learning. Vector …
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Special Initiatives & Programs
… synthesis, and targeted metabolomics support for DOE-BER funded awards, including awards funded through  BER Funding Opportunity Announcements ,  Science Focus … Office of Science Early Career Research Program .   If “BERSS” is not mentioned in the BER funding call, proposals …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… has established a portfolio of microbial hosts that users can select to be engineered. “Piloting access to this … users will enable us to assess CRAGE’s impact, including how this application could scale,” says Mouncey. The JGI … of DNA that can be inserted at a time. In a  project detailed in  ACS Synthetic Biology , Yoshikuni and …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… in the lab. To access the genomes of uncultured  microbes , scientists usually employ two different methods; … studied with MDA. With the introduction of PTA, JGI users can get more complete single-cell genomes more consistently. JGI users can request this capability when  submitting a proposal . …
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Doubling Down on Known Protein Families
… to see beyond the beam — worse, they didn’t even know how big the room is.  A new study  published online Oct. 11, … the Novel Metagenome Protein Families (NMPF) Catalog.  “We can now analyze new datasets by comparing against these … a DOE Office of Science User Facility  located at Lawrence Berkeley National Laboratory, is committed to advancing …
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SIPs with Standards
… for studying microbial communities. These experiments can show which microbes are handling specific nutrients, or what they're doing …
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JGI@25: Building a Better Bean
… the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable great … popular food in Central America and Eastern Africa. For smallholder farmers — those with less than two hectares of …
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JGI Workshops at PAG
… of the length and breadth of algal diversity, the numbers of sequenced algal genomes, and the quality of those … to BER funded activities of plant systems. We will describe how to apply for a project with the JGI Community Science Program and how you can use the KBase system to accelerate your plant genomics …
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The JGI Data Portal: Improving User Experience
… The human-centered, agile collaboration between the JGI and the information technology company Truss … to download is a complex one, so our joint team started small, in the tradition of agile design and development,” … for various data types or taxa An at-a-glance view of how much data you’ve selected for download, as well as …
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Annual Genomics of Energy & Environment Meeting
… gathering of leaders from diverse disciplines to highlight how they are addressing the world’s most pressing energy and … peer-reviewed basis to the worldwide scientific community can advance your research goals. Keynotes: M. Francesca … Cotrufo, Colorado State University N. Louise Glass, UC Berkeley Ian Foster, Argonne National Laboratory Sue Rhee, …
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