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Enlarging Windows into Understanding Gene Functions
… of the alphabet. Yet the specific sequence of these four letters represents an organism’s genetic code, or … encoded in the genome sequence is part of the integrative science mission of the U.S. Department of Energy (DOE) Joint … as DNA affinity purification sequencing or DAP-seq. The technology was developed by Ronan O’Malley , who leads the …
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Prepublication data sharing
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Clustering Categorical Data
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JGI Welcomes New UEC Members
… input and advice on JGI policies and practices that affect users and their access to technical capabilities JGI offers, … for three additional positions on the UEC. Seventeen JGI users were nominated, representing a breadth of … the scientific areas of plant genomics, DNA synthesis and metabolomics, respectively. To view the full roster of …
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Supporting Global Research into Actinomycetes
… Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, as well as a member of  its Secondary … user-available API’s offer a space to not just store data, but for the community to discuss those data and make … Prodcast podcast , where she talks about this community resource. ) “Most people study actinomycetes because they …
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A Community Resource for Secondary Metabolite Researchers
… The Secondary Metabolism Collaboratory encourages user engagement. The Science In addition to the core set of "primary … metabolites are useful in a variety of fields including biotechnology, medicine and agriculture. This comprehensive … Institute (https:// ror.org/04xm1d337), a DOE Office of Science User Facility, is supported by the Office of Science …
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An Enzyme System to Help Catalyze Bioproduction of Plastic
… For bacteria, that salty, slightly stinky air is a rich source of the sulfur they need to grow and divide. Similar to … Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … with understanding enabled by Basic Energy Sciences (BES) programs, they were able to multiply the insights that each …
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Marchantia Pangenome Highlights Adaptive Nature of Plant Lineages
… genetic toolkit of ancestral and present-day plants The Science In a recent  Nature Genetics paper , researchers … Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … of the  Marchantia pangenome, scientists developed a resource that associates plant’s genetic variants with specific …
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Cultivating Symbiotic Antarctic Microbes
… they are symbionts and not free-living organisms. The Science Researchers employed multiple microbiology and … interactions. Using metagenomes recovered directly from environmental samples and cultivated microbes, … host cells. In the  Proceedings of the National Academy of Sciences , a team led by Rick Cavicchioli at the University …
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The Fast Changing Landscape of Sequencing Technologies and Their Impact on Microbial Genome Assemblies and Annotation
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iPHoP: A Matchmaker for Phages and their Hosts
… computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do … nutrient cycling, or carbon sequestration. Summary Existing programs use a variety of approaches to match a virus with a … used 1,870 known virus-host pairs to generate a matrix of data points.  Applied to 216,015 high-quality virus …
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Boosting Small Molecule Production in Super “Soup”
… Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … able to make the same amount of a product in just eight hours that growing cells take three days to make, which is a … said. “We’re exploring not just what can be enabled by this technology, but also what we can understand through this …
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