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… Leveraging massive comparative genomics to decode millions of mystery genes and lay a future-ready foundation     Over … plant and animal genomes can sprawl across billions of DNA base pairs, most fungal genomes contain fewer than 50 … accompanied by hypotheses about fungal lifestyle and their roles in ecosystems.” The JGI's comprehensive genomic …

… about natural products and the science and scientists of secondary metabolism. Natural products, secondary … species unique and different from one another. They are incredibly important to medicine, the environment, and human … research, “Natural Prodcast” serves as an important line of communication to the scientific community. Host Dan …

… Novel archaeal lineage found in Yellowstone may have been important in early Earth conditions. The Science Through a combination of sequencing tools and techniques applied to samples … generating thousands to millions of copies of a particular DNA sequence from just a few pieces of DNA. Summary The …

… In April 2020, we mark both the 50th celebration of Earth Day on April 22, and DNA Day on April 25. As both Earth and DNA are close to our … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …

… Accepted proposals emphasize JGI interests in algae and secondary metabolites. A total of 27 proposals have been  approved through the annual  … in algal research for bioenergy production and algae’s roles in nutrient cycling, now a facet of the  Fungal & …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … to provide colleagues at the Salk Institute with genomic DNA samples from Ruminococcus flavefaciens (XPD3002). With …

… Researchers looked across many organisms to see that aminotransferase enzymes have evolved mix-and-match … characteristics — creating many different ways of processing nitrogen. To boost crops more efficiently in … analysis of the AT enzyme family, the JGI provided DNA synthesis capabilities to enable functional testing of …

… This year’s list features 6,900 researchers working in 21 fields.  Congratulations to the  2022 Highly Cited … in their chosen field or fields through the publication of multiple highly cited papers during the last decade” by … Tanja Woyke (Biology and Biochemistry)  Here’s a selection of studies these busy bees contributed to:  Giant bacteria …

… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a … sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized these sgRNAs, cloning …

… With a new methodology, scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … years, extracting single cells and then amplifying their DNA for genome sequencing was no easy task. The traditional …

… Cas14 proteins discovered from JGI’s IMG/M database and biochemically … Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short … associated proteins that can target single-stranded DNA (ssDNA). The discovery was made possible by mining the …

… Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages … in  Microbiome , researchers from the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …