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Extracting the Secrets of Secondary Metabolites
User Facility, is supported under contract DE-AC02- 05CH11231. …
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Gut Fungi: Unexpected Source of Novel Chemicals
Research and operated under Contract Nos. DE-AC02-05CH11231 (JGI) and DE-AC05-76RL01830 (EMSL). CLS is also supported by a National … Graduate Research Fellowship Program under Grant No. 1650114, a UCSB Graduate Division Dissertation Fellowship, and …
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From Berkeley to Binghamton: Tracking Strawberry Evolution
In the summer of 2015, Adam Session was a postdoc working at the DOE Joint …
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New Research Sheds Light on Diversity in the Deep Sea
… the ocean through vents at temperatures that can exceed 750 degrees Fahrenheit. The minerals in these fluids include … function in such extreme conditions. They identified 511 new or recently discovered genera of bacteria and … Science Foundation grants OCE-0728391, OCE-0937404, OCE-1558795 to A-L.R, and OCE-2049478 and DBI-2047598 to K.A. We …
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The More the Merrier: Making the Case for Plant Pan-genomes
… more than once, and these events took place a million years apart: the individual with a maternal  B. distachyon parent (D plastotype) some 1.4 million years ago (Mya), while the S plastotype was a more recent … anticipated with only minor gene loss even after a million years.” Reference genomes for  B. distachyon ,  B. stacei …
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The JGI announces FY25 awardees for our Community Science Program Annual Call
… excited to announce the 18 scientists selected for our 2025 Community Science Program Annual Call. These projects … outcome of the innovative research  being proposed by this year’s CSP investigators,” said Tanja Woyke, Deputy Director … here on our website.   See below for the full list of 2025 CSP Annual Call awardees. …
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Doubling Down on Known Protein Families
… we’ve already defined.  “A huge percentage — around 30–50% of the protein families that we knew so far — still does … but we knew the families,” Kyrpides said. Yet, “almost 20 years of metagenomic data and metagenomic analysis, and … of new protein families had started to plateau in recent years, perhaps suggesting that scientists had “captured” …
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The Power of One, Amplified
… large-scale single cell genomics by collecting nearly 500 single cells from a single low diversity hot spring … in, on, and around the planet remain unknown. In recent years, advances in sequencing technologies and bioinformatic … diverse than those within more moderate ecosystems. A few years ago, a candidate bacterial lineage was identified from …
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Enlarging Windows into Understanding Gene Functions
Technologies Group. In an article published November 25, 2021 in Nature Methods , JGI researchers led by co-first … ENCODE project known as FUNCODE. “We noticed a few years ago that there is no shortage of fungal genomes … functional interpretation is as tough as it has been 10 years ago,” he said. “We thought about reconstructing gene …
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Jane Grimwood Named HudsonAlpha Genomics Chair
… the simplest cotton genome ( Gossypium raimondii ) several years ago.   As well as the seminal Human Genome Project DOE … DNA sequence and comparative analysis of human chromosome 5 The sequence and analysis of duplication-rich human …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… rely on enzymes that have been evolving for billions of years. However, these enzymes are often loosely understood, … enzymes across 90 species. They queried the genomes of 15 species from each of six kingdoms: eubacteria, archaea, … that even enzymes that evolved separately for billions of years have some common signatures of muli-substrate …
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A Community Resource for Secondary Metabolite Researchers
… expediting BGC and biosynthesis research.  Summary Over the years several secondary metabolites databases have been made … of Science of the U.S. Department of Energy [DE-AC02-05CH11231]. … SMC is the most comprehensive BGC database …
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