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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… With a new methodology, scientists are now getting more complete … single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome … stitch the pieces together and attempt to put them back into the original genomes. These metagenome-assembled …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… A special issue of Synthetic Biology celebrates research … cell is key to interrogating what genes do, how they work, and applying them to environmental and energy challenges. … more than 10 papers, including two Nature Plants publications, in five years, have come out of the …
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An Automated Tool for Assessing Virus Data Quality
… CheckV can help researchers assess virus sequence fragments and data … picture of a virus, and for viruses that have integrated into the host genome, these sequences may be tainted by the … suite, as well as sequences from the Global Ocean Virome 2.0 dataset based on open ocean samples. CheckV identified a …
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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
… Streamlined genome with precise gene targeting transforms oil-producing alga into a powerful platform for developing ​​bio-based … This work was supported by the Department of Energy (DOE) Office of Science, Biological and Environmental Research program under award no. …
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Taking Stock of the Known and Unknown Microbial Space
… Metagenomic datasets could help map out microbial diversity hotspots Over the past few decades, advancements in sequencing technologies have led to an … and cultivate what is still unknown.  “We took a deep dive into over 1.8 million bacterial and archaeal genomes to see …
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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and … the power grid of gene regulation is finally coming into clear view. Behind the Breakthroughs: Advancing gene … Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE Office of Science …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… As SIP experiments shed more light on microbial communities than ever before — especially with the prospect of … Stable Isotope Probing (SIP) has opened vast windows into specific activities catalyzed by microbial communities. … Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE Office of Science …
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The Surprising Structure of a Shrub Willow Sex Chromosome
… A genetic architecture that is characteristic of the sex … chromosomes of mammals is, for the first time, seen in a plant. The Science Sex in plants can be befuddling. Most … strategy we are far more familiar with: differentiating into male and female sexes. For the first time, the sex …
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Virus Discoveries that Keep Getting Bigger
… Sequence-based studies — from metagenomics to single-cell work — have quickly accelerated understanding of giant viruses. The Science In the last thirty … have used culture-independent approaches to gain insight into the  genomes of giant viruses. In a new review, …
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Characterizing Communities: JGI Announces Latest CSP Portfolio
… Proposals aim to sequence and annotate genomes from Antarctica to … Crambe hispanica ,  Brassica oleracea , and  Streptanthus barbigeri (bearded jewelflower). Part of efforts to develop … Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE missions related to clean …
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Four Researchers Join JGI User Executive Committee
… Four researchers have been elected to the User Executive Committee of … Bik of the University of Georgia, Greg Bonito of Michigan State University, Jonathan Eisen of the University of … we thank them for their advice. Christopher Schadt stepped into the UEC chair role effective March 3; Lizzy Wilbanks …
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… Sequencing technology has changed dramatically over the last  25-plus years since … large-scale assembly and analysis.   To put these efforts into perspective, we caught up with JGI staff, collaborators … Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE missions related to clean …
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