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Enlarging Windows into Understanding Gene Functions
JGI innovates protocol revealing how genetic variations in sequences … sequencing or DAP-seq. The technology was developed by Ronan O’Malley , who leads the Sequencing Technologies … what TFs and regulatory networks are conserved across fungi.” Using multiDAP-seq, Nagy’s team is comparing five …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
As SIP experiments shed more light on microbial communities … example, SIP experiments can show how soil microbes cycle nitrogen and carbon, or how freshwater ecosystems process … Even better, creating comparable data with useful and accessible metadata multiplies these possibilities, and …
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Fields of Breeders’ Dreams: A Team Effort Toward Targeted Crop Improvements
Gardeners and farmers around the country recognize that crop … As  reported January 27, 2021 in  Nature , the team led by researchers at the University of Texas (UT) at Austin, … adaptability to various environmental conditions. “To accelerate breeding for  bioenergy , we need to make …
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Len Pennacchio
In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused … in human and mouse triglyceride metabolism. He is funded by DOE and through continued competitive grant support from …
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Jane Grimwood Named HudsonAlpha Genomics Chair
Congratulations to Jane Grimwood, who has been appointed the Loretta Purdy … was a group lead at Stanford Human Genome Center directed by Richard Myers, and among the Center staff that moved to … sequence of the complex switchgrass genome , using samples from common gardens growing across the country. The …
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Waiting to Respire
Genomes from uncultivated bacteria offers clues to ancestral … ability to produce their own food and generate oxygen as a byproduct. The abundance of oxygen shaped the evolution of … Melainabacteria and Sericytochromatia, members of the same clade as Cyanobacteria, applied strategies other than …
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Tracking the Origins of Methane-Producing Microbes
Mini-Metagenomics Approach Helps Identify Novel Archaeal Methane Metabolism. … The archaeal genome was detected in samples collected by Stephen Quake’s team at Yellowstone National Park’s … history of the different types of methanogenesis occurring in the entire archaeal domain of life.” … The U.S. …
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Applying Viral Genomics Expertise to Understanding the Human Virome
JGI researchers lend expertise to develop tools and data hub for … the stars in the Milky Way, viruses outnumber the microbes by at least another order of magnitude. For years, … Consortium Organization and Data Collaboration Center (CODCC), is led by a team of highly experienced investigators …
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Introducing New Members of the JGI User Executive Committee
The JGI welcomes three new members to their User Executive Committee (UEC) … ecologist Gilbert at the University of California (UC) San Diego, being on the UEC is an opportunity to help … She aims to help overcome common user bottlenecks in access, analysis and sharing of JGI-generated data. She is …
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Expanding Virophage Diversity
Virophages are small viruses with double-stranded DNA genomes that … genome sequences 10-fold through computational approaches. By mining more than 14,000 publicly available metagenomic … sequences.  Further analysis led to the identification of 328 “high quality” (based on completeness) diverse new …
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Calculating the Costs of Multiple Switchgrass Gene Copies
Scientists have discovered that the candidate bioenergy … habitat range. But at what cost?  A collaborative team led by researchers at the University of Texas (UT) at Austin, … a changing future. Switchgrass has multiple naturally occurring ploidy levels, called cytotypes, across the …
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The Expanding Universe of Methane Metabolisms in Archaea
Metagenome-assembled archaeal genomes provide new insights into an … Microbial Genomes & Microbiomes (IMG/M) database maintained by the U.S. Department of Energy (DOE) Joint Genome … possibly at ~3.5 Gy (billion years),” Borrel and Gribaldo said in an email. “Therefore, determining under which form …
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