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Extracting the Secrets of Secondary Metabolites
… combo helps further demystify biosynthetic gene clusters.  The Science Microbial secondary metabolites, those … and other industries — yet there’s still so much about them we don’t know.  Unlocking the power of secondary … CRAGE allows for the transplanting of these BGCs from one organism into an alternate host via a landing pad …
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Micro-Scale Applications Group
… Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new … microbiome activity levels.This functional assay lets us move beyond cataloging the genes of microorganisms and …
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Open Frameworks Training the Next Generation of Scientists
… technologies provide opportunities for students and professors alike The Science In  PLoS Pathogens , a team of … participants. Over the past two years, Myco-Ed has been used in 15 individual classrooms across the country, … readily available via the KBase platform. This effort grew from a  modularized training program with the aim for future …
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New Research Finds Flagella in the Terrestrial Roots of Marine Bacteria
… in an unexpected place: hot spring-dwelling bacteria from the phylum C hloroflexota . Research shows that … microorganisms for biofuel production and other sustainable applications. Summary Hot springs are … Genome Institute, a DOE Office of Science User Facility at Lawrence Berkeley National Laboratory, has unveiled these …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… carbon and cycle key nutrients like nitrogen and phosphorus.  This way, the fungi of forest soils hold keys to tree … three different fungal guilds in a range of different locations. They sampled soils in four forest ecosystems, … give researchers a way to access much more information about fungi in these environments. “Now with these new tools …
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A One-Stop Shop for Analyzing Algal Genomes
… an interactive browser that allows algal scientists and enthusiasts to look deep into more than 100 algal genomes, … and what they do. Summary The name PhycoCosm stems from the Greek phykos, meaning seaweed. Seaweeds are algae, … (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab), have …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… health. Three DOE national labs had people and resources focused on three human chromosomes: Lawrence Berkeley National … researchers were studying Chromosome 5, which contains about 6% of the human genome . They discovered genes linked … years. The DOE brought together the people and resources from these three national labs to form the DOE Joint Genome …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but … (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory, is heavily invested …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… first paper that describes sorghum’s response to drought, from a large-scale field experiment to uncover the … (UC), Berkeley, UC Agriculture and Natural Resources (ANR), US Department of Agriculture P­­lant Gene Expression Center, … (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab).     …
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Silver age of GOLD introduces new features
… 25 years ago, the  Genomes OnLine Database has matured from six projects on a spreadsheet into a flagship  genomic … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab), but …
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New and Improved: Eucalyptus Reference is Now Accessible
… Researchers report a new reference genome for eucalyptus in the July edition of the journal G3 Genes | Genomes | … it separately represents the sets of chromosomes inherited from each parent. It also has 700-fold greater contiguity, … (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory.  Now, enabled once …
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Environmental Genomics Group
… Research in the Eloe-Fadrosh group focuses on using genome-resolved metagenomic approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial …
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