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Better Genome Editing for Bioenergy
… included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … a team of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s … a pool of sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized …
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Cataloging the Microbes that Manage the Health of River Systems
… 90% of US continental watersheds. The Science In a recent Nature paper , researchers describe a dataset of microbial genomes sampled from rivers covering 90% of the watersheds …
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Expanding Virophage Diversity
Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant … Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant … author David Paez-Espino  discussed an early version of the paper at the 2018 Viral EcoGenomics & Applications (VEGA) …
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Refining the Process of Identifying Algae Biotechnology Candidates
… multiple institutions have sequenced and analyzed the genome of an alga that thrives in saltwater (halotolerant) … such as arable land and fresh water. Summary On the list of candidate bioenergy feedstocks, algae are tiny but … researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Fields of Breeders’ Dreams: A Team Effort Toward Targeted Crop Improvements
… of the United States. As  reported January 27, 2021 in  Nature , the team led by researchers at the University of … and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … collaborators, and collections at other field sites. “This paper is a combination of really cutting-edge genomics and …
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Marine Microbe Contains Multitudes
… and colleagues set sail on research cruises in 2015 and 2016. At Station ALOHA , site of the 30-years-long Hawaii … periodically at different depths. In order to determine the genome structure of SAR324 cells and their gene expression, the team then sequenced community genomes and expressed gene transcripts (metagenomes, …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… enabled by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … by methanogenesis. Both studies were recently published in  Nature .  Researchers started by collecting samples from … the original methanogens were, but they were discovered by genome sequencing, which is a much less biased approach to …
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A Community Resource for Secondary Metabolite Researchers
… over 1.3 million publicly available bacterial and archaeal genome and contig sources.  The Impact Secondary metabolites … or tools. The U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … metabolites portal within the Integrated Microbial Genomes and Microbiomes (IMG/M) system known as IMG-ABC. …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for … most species do not grow easily in the lab. To access the genomes of uncultured  microbes , scientists usually employ … extracting single cells and then amplifying their DNA for genome sequencing was no easy task. The traditional way of …
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Trent Northen
Northen’s research is focused on using metabolomics to link genomes with environments to understand how webs of microbes … survey of Populus across genotypes and environments. 2024 Nature Sci Data. 11, 339. … Biosciences Inventor of the Year 2019 R&D100 Award 2016 Berkeley Lab Director Exceptional Achievement Award …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… collaborated with the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … Annotation Group. Many of these bacterial and archaeal genome sequences have been generated using techniques that … Repertoire in Actinobacteria Over the years more than 3,400 genomes have been sequenced from curated DSMZ isolates, for …
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Celebrating a Decade of Science through the JGI-UC Merced Genomics Internship Program
… of the flagship internship program between the DOE Joint Genome Institute (JGI) and University of California (UC), … scientist and program mentor, discussed how “advocating and listening to the interns and learning their perspectives and …
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