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… genomic information from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct … Our research focuses on the assembly of metagenomic sequence data into microbial genomes, which is of …

… and written pretty close to the level of technical detail that I think we’re doing here. If you have suggestions for … able to explore DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less …

… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … general feasibility prior to submitting a BER proposal that includes a JGI request.  Proposals whose scope was not … for sequencing, as long as they have a scientific question that is relevant to DOE missions.  Learn more about this …

… in firmly in the chemistry bucket. [LAUGHS] I don’t know that that’s ever necessarily like a good description of … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … decade or so. He’s involved with a lot of the common tools that genome miners use, including antiSMASH, MIBiG, and … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …

… since I’m off schedule, but this is an important one that wanted to get out there as soon as possible. Not one of … is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …

… For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on a regular basis, in accordance with …

… in one research proposal.  Submit research proposals  here that integrate genomics with nanoscale science, accelerating … and developing transformative bio-based technologies that address challenges in the sourcing, recovery, and … shipping; JGI will handle all subsequent processing from that point. JGI provides users with various outputs free of …

… a computational pipeline to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring … of white. To researchers searching for sequences of RNA viruses in large data sets, their work may be akin to … to defend against RNA,” Roux noted, “although it’s unclear why this is so rarely detected.” Developing Approaches for …

… expands the global diversity of large and giant viruses. While the microbes in a single drop of water could … Lab) uncovered a broad diversity of large and giant viruses that belong to the nucleocytoplasmic large DNA viruses … genomes of uncultivated giant viruses from environmental sequences across the globe, then using these sequences to …

… Sequence-based studies — from metagenomics to single-cell … work — have quickly accelerated understanding of giant viruses. The Science In the last thirty years, in … a microeukaryote, forms large algal blooms in the ocean that cycle environmental carbon and sulfur. A giant virus, …

… this whole “on-time thing” a habit! I’m really not good at that, you guys. I’m trying really hard just for you. And the … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …