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… Below is a brief description of the process needed to prepare and ship samples for … sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and quality has been the rate-limiting … step for many projects at the JGI. The quality of the starting material is one of the greatest predictors …

… Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and … and their roles in the environment, can unlock new avenues for bio-based products and bioenergy crop …

… other things. And we know lots more about microbiomes and symbionts that live with other organisms, and often it’s the … DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … right. So I did a PhD in microbiology at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so …

… Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … advances in management, processing and visualization of “big data,” and artificial Intelligent/machine learning … approaches in data analysis and interpretation is creating new opportunities for breakthrough discoveries and …

…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national … at Lawrence Berkeley National Laboratory. The JGI consists of 225 researchers and support staff in the Integrative … from plants, fungi, algae, non-medical microbes, microbial communities, and other relevant organisms. We …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

… expertise and infrastructure enable a broad community of scientists and engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data discoverability and … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic …

… Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the … And sometimes, in terms of biological activities– like antimicrobial or something– sometimes a little difference is …

… the user programs at the JGI, and I’m also the head of the microbial genome program. And I’m a scientist here. And have … at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … IMG kind of hooks into IMG’s data. IMG being Integrated Microbial Genomics at JGI, a large data set of bacterial …