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…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a … at Lawrence Berkeley National Laboratory. The JGI consists of 225 researchers and support staff in the Integrative … organisms. We provide access to large-scale datasets and analysis tools for genomes, metagenomes, and metabolomics …

… Data produced and released by the US Department of Energy (DOE) Joint … data. The JGI Data Policy applies to research data and analysis products (referred to as “data” for the remainder … is granted to proposal PIs, Co-PIs, and collaborators of any given proposal. Third parties (often referred to as …

… The purpose of this policy is to establish communication norms around … (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any other contributions, such as assembly, analysis, annotation, verification, creation of genome …

… Biology is currently experiencing a revolution brought on by rapid … and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … artificial Intelligent/machine learning approaches in data analysis and interpretation is creating new opportunities …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to … done a lot of work learning about how to use statistical analysis to prioritize both to analyze our bigger system …

… The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … unknown. And so we've done the sequence similallity network analysis where we look for other receptors with sequence …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … ALISON: Hmm. It kind of – it’s kind of like I’m smelling bacterial perfume. I mean – but it’s purposeful so it’s some …

… Research in the Woyke laboratory focuses on the utility of single-cell … our skewed understanding of microbial metabolism towards a minority of cultivated bacteria, still persists to … is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which …

… out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk … Then you have to maybe improve some of your bioinformatic analysis. You don’t want to get clusters that are encoding …

… The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, … plants and microbes, and understanding microbiome interactions. The  insights derived are crucial for … a combination of experimental workflows and computational analysis, JGI scientists are able to link metabolic activity …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …