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… processes, development of high performance plants and microbes, and understanding microbiome interactions. The  … mass spectrometry-based methods to analyze metabolites from a wide range of biological and environmental samples — … communities, and samples including state-of-the-art instrumentation and informatic approaches.By bridging genomics …

… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, …

… week, we have our conversation with Professor Eric Schmidt, from the University of Utah. I’ve known Eric for a long time … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… activity. So the chemistry and function really of those microbes that live there.  And in our work we’ve determined … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

The ranked proposal list, along with a recommendation from management at JGI and the other participating … … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on a regular basis, in accordance with …

… of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. … ecology community to be able to better predict how their microbes are interacting with each other from sequence …

… what’s important in terms of the chemistry produced by microbes. And by what’s important, I mean, like, where … Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …

… in the analysis and publication of the claimed genome sequences. This opportunity, provided by the Department of … builds upon thousands of microbial genomes that have been sequenced by the JGI though not formally analyzed or … … A primary purpose of this project is to bring educators from a broad range of disciplines up-to-speed with some of …

… culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or whatever. And so I was … and take soil and discover a new important drug from the microbes in that soil, there are now international … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … where smaller proposals may be a fit. Still not 20 many microbes. We still we work in plates, right? We’re a high … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …