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… A global metagenomic map of urban microbiomes and antimicrobial resistance. Cell . 184(13):3376-3393 Almeida A, et … al. (2017) Protein structure determination using metagenome sequence data. Science   355(6322):294-298 Paez-Espino D. et … reveals a new bacterial candidate phylum in geothermal springs.  Nature Commun. 7:10476 Varghese NJ,  et al. …

… and I were lucky to get some time to sit down and have a great chat with him.  I kind of lost count of how many times … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against …

… get a new one out every two weeks. This time, we’ve got a great interview with Ben Shen, from the Scripps Research … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

… from plants, fungi, algae, non-medical microbes, microbial communities, and other relevant organisms. We provide access … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … went on to advance basic science by sequencing scores of microbial species as well as several model organisms and …

… Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our … access to cutting-edge cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated … To provide additional functional insights into microbial genomes, the JGI now uses laser microdissection to …

… including fungal and bacterial symbionts, detrimental microbial pathogens, and associated viruses that all … how plants self-organize, influence, and are influenced by microbial partners. We use a variety of genomics-powered …

… phylogenetic tree without cultivated representatives. The “Great Plate-Count Anomaly” first described by Stanley and … in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of cultivated … is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which …

… this we’re going to be spending some time talking some great scientists, who all have really interesting stories … able to explore DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less …

… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … byproducts from lignin left over after biomass processing. Great Lakes Bioenergy Research Center , led by the … breakthroughs in basic science, and is exploring microbial-based synthesis of fuels beyond ethanol. …

… parameters driving virus:host dynamics in environmental microbial communities. This involves both experimental and … invaluable information on virus diversity and activity in microbial communities, however they can only provide a signal … is driven by snowmelt and host dynamics in a high-altitude watershed soil ecosystem. Microbiome 11, 237. …

… DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have … we’re all here together. ALISON: How beautiful. What a great partnership.  DAN: Yeah, I guess so. You know, it’s …