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… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …

… Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for … of the JGI User Agreement , JGI User Agreement for Federal Agencies , DNA Synthesis Appendix  and DNA …

… The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the biological …

… of secondary metabolism.  DAN: Hello, and welcome back for Episode 7 of the Natural Prodcast. It’s been about a … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

… so secondary metabolism is throughout nature, except maybe for animals and humans, not as much. You know, we have this … DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …

…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national … at Lawrence Berkeley National Laboratory. The JGI consists of 225 researchers and support staff in the Integrative Genomics Building in Berkeley, California.  Our location at the IGB fosters team science and …

… Data produced and released by the US Department of Energy (DOE) Joint Genome Institute (JGI) are subject to … Data Policy. It is our mission to support open data and information sharing. We also recognize the need to have a … research data and analysis products (referred to as “data” for the remainder of this policy) produced through all user …

… sequencing, synthesis, and targeted metabolomics support for DOE-BER funded awards, including awards funded through  … ,  Science Focus Areas  (SFA) opportunities, and the  Office of Science Early Career Research Program .   If … capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA …

… technologies to the broader community.  We focus our efforts on integrating database mining and sequence design with scaling the production of large, … and understanding the design principles for successfully engineering pathways to function in heterologous hosts, by …

… I think it must’ve been about 2001, maybe, and so it was before smartphones and before laptops and everything. And I … Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …

… It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for the … at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …