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Natural Prodcast Episode 20: Brian Bachmann
… And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … of thought with that. So some people are interested in cave microbial– people are interested in the more extreme …
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A Grass Model to Help Improve Giant Miscanthus
… Miscanthus  sequence offers insights into benefits of polyploidy and … genome sequence and genomic toolkit for the perennial grass Miscanthus sinensis has been published. Analysis of … abilities to adapt to extreme environments such as poor soils and drought. The reference genome for M. sinensis, and …
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Natural Prodcast Episode 4: Nancy Keller
… That has a lot to do with, well, the fact that it’s a eukaryotic genome, I guess, and the way DNA is activated. … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk …
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Metabolomics Program
… The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our understanding of genome science, organisms, and ecosystems at the … exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With …
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Natural Prodcast Episode 7: Ben Shen
… the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very … genomic revolution, to me, as a natural part chemist for microbial natural product, is that I love microbial natural …
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Single Cell Research Group
… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is … in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of cultivated …
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Natural Prodcast Episode 2: The Primer, Part 2
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …
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Examples: Successful LOIs & Submissions
… See below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, … Microbial contributions to soil carbon storage during simulated range shifts of plant-fungal symbionts … Elucidation of the gene regulatory networks governing terpenoid-mediated …
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JGI Portals
… expertise and infrastructure enable a broad community of scientists and engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data discoverability and … the JGI will move to a new login service, requiring the use of an ORCID account with two-factor authentication enabled …
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Natural Prodcast Episode 19: Bill Fenical
… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … powerful people. These were people that really controlled microbial drug discovery. And a guy like me, with no … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …
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Natural Prodcast Episode 21: Elizabeth Parkinson
… outreach program to get kids interested in microbiology and microbial chemistry. All good stuff, and I hope you enjoy … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …
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FICUS-NERSC/KBASE
… The mission of the Joint Genome Institute is to serve the scientific … relevant bioenergy and environmental problems.  The mission of the National Energy Research Scientific Computing Center … ( NERSC ) is to accelerate scientific discovery at the DOE Office of Science through high performance computing (HPC) …
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