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… SPPs enable research funded by an industry partner to perform a defined … CRADAs enable research jointly sponsored by Berkeley Lab and one or more … our User Program’s Community Science Program, the JGI sequenced and characterized 270 genomes of the Clostridium … Cooperative Research and Development Agreements …

… on Facebook about cinnamon or turmeric curing every disease and helping you sleep at night (I’m not sure if that’s … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … as we go on, so if you hear a topic you’d want us to dive deeper on, let me know! All right, so here we go. This is …

… opportunities, and the  Office of Science Early Career Research Program .   If “BERSS” is not mentioned in the BER … capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … The JGI is inviting researchers using the U.S. Culture Collection Network (USCCN) …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … all based on antiSMASH results. And so if you want to do deeper analysis on things, then you’re staying in the “BiG” …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … Maybe if you could talk about what your– I don’t know– research background pedigree is. I hate to like sort of like … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …

… nuclear security, energy production, and scientific research, especially at US National Labs, like Lawrence … at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

… large-scale genomic data to advance microbial research that drives sustainable solutions in energy, … The program also studies giant viruses. Key research areas include terrestrial biogeochemical cycling and … efforts will provide valuable data for further microbial research and applications. One key program goal is focused on …

… DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … – how bacteria or other organisms communicate and how and why secondary metabolites are being produced in the … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …

… Colorado State University GI users and microbiome researchers Mike Wilkins and his graduate student Kaela … have many questions about the microbial communities deep underground, and before the pandemic, they took the JGI … for User Science (FICUS) . Through FICUS, the researchers have tapped into the resources and capabilities of …

… Institute's Biodesign Platform capabilities support researchers exploring how to convert sequence into functional assessments. This is done by … and quality control Strain Engineering Group : a research & development group and focused on new technologies …

… with Nancy Keller, a fantastic fungal natural products researcher from the University of Wisconsin. Like we discussed … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk …

… The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … I think, discovered in E. coli, but we can utilize blast searches or other things like that in order to find them. … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …