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… approaches to assess microbial activity across ecosystems.  By studying microbial communities and their interactions, … based on functional traits. These advancements provide new insights into microbial ecosystems.  The Program also … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …

… hard it was – it felt kind of like training for a marathon by running at a high altitude! And a lot of us moved on to … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

Science Program , or CSP, which is the main mechanism by which users work with our facility to do science. Since I … at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … just– and then in terms of there’s sequencing an organism by shotgun, which is what we did, we didn’t even sequence …

… more about Tiny Earth and the JGI’s role in the project by watching Amanda Hurley’s presentation from the 2019 JGI … at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

Call, as well as successful submissions to our CSP New Investigator, CSP Functional Genomics, and Facilities … … CSP Large-Scale LOI #1 … CSP Large-Scale LOI #2 … CSP New Investigator Submission … CSP Functional Genomics …

Biodiversity Groups, and it’s this great program funded by the National Institutes of Health and the National … Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … introduction in natural products, so I might just start out by asking you know how did you get started. I know you’re … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. …

… next review cycle. All proposals undergo technical review by JGI staff as well as staff at the other participating … … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on a regular basis, in accordance with …

JGI has a strong interest in seeing that the data produced by the facility result in scientific publications. JGI users … (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any other … navigate to the proposal info page using any of the below methods: Search the Genome Portal Navigate to the JGI Genome …

The program employs advanced mass spectrometry-based methods to analyze metabolites from a wide range of … state-of-the-art instrumentation and informatic approaches.By bridging genomics with metabolomics, the Metabolomics … liquid chromatography mass spectrometry (LC-MS) based methods in combination with advanced computational …