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… archaea, and micro-eukaryoes, along with their associated viruses and mobile genetic elements. Beyond exploring and … govern ecosystem processes. This research provides insights into microbial diversity and metabolic potential, with implications for energy production, environmental sustainability, and …

… I wanted to start, maybe just by asking you how did you get into the field of natural products?   NANCY: Yeah, that’s a … I like with fungi is, because they’re complex, they have different tissues, different structures, different spores. I … out – expressing the quiet clusters and then trying to figure out why, even if you express them, you’re not getting …

… Bill is a pioneer of marine natural products, getting into the ocean and looking for molecules from the very … our ability. And ultimately we went through a whole lot of different processes with plants and animals, really, all … that the molecules out there would be toxic to cancer cells. And that started something big. Because at that time, …

… good at finding and killing plants, so if you haven’t figured that out already from the book, not so great at … always wanted to write a book but it’s really hard to break into that area. I mean you have to secure an agent and … bit of an unusual kid too because I was born with a lot of different birth defects of my skeletal system. So I was …

… episode with her in the near future where we can dive into that. And I’m also dying to talk in more detail about … Yeah, well, there’s a lot of– there’ s a couple of different schools of thought with that. So some people are … a single cell level against cell lines and against primary cells isolated from patients up to 12 markers at a time. And …

… marine natural products chemist, Richard Moore, and get into seaweed, robots, algae, and biocatalysis — and he makes … him? I know a lot of people sort of veer off and go into different directions. Brad: Absolutely. You know, my father … or they can store that chemical – or they can store the cells, as well. And so we’re hoping initially to be able to …

… inter-organismal interactions. These insights are crucial for addressing key environmental challenges, such as … with microeukaryotes. The program also studies giant viruses. Key research areas include terrestrial … and inter-organismal interactions, which are critical for advancing sustainable solutions in agriculture, energy …

… that a lot of people want to answer again from a very different standpoint or from very different angles, right? … than it is now. Or a little more– yeah, put more rationale into drug discovery by knowing what these things actually do … even in primary metabolism or in certain snips of viruses or something. I don’t know. Then I think making sure …

… basic ideas of the science of natural products, and we dive into the very early history of the field. If you continue … cell.  DAN: It depends on lifestyle. So there are lots of different organisms that produce secondary metabolites for … like, you know, like an organism. They have specialized cells and the ecology there is really fascinating, probably …

… can visit the Products & Offerings section of our website for more details, including a downloadable pdf of products … come from the user community. Find out about JGI’s calls for proposals , and submit your proposal online using the Work Initiation Process (WIP) interface.    For commonly asked questions about JGI’s proposal calls and …

… also, I thought you were a good representative of maybe a different career trajectory than we sometimes see… MARC: … So maybe we could start with that background – what got you into secondary metabolism, besides being forced to work with … does it take to become a hub? MARC: We’re still trying to figure that out. I mean, we’re still quite new. I joined as …

… that we’ve had on this podcast, the idea of taking all the different natural products data that there is and putting … question. Kate, can you tell me the story of how you got into secondary metabolites? Kate Duncan: So I always liked … spec– but I find it really interesting to sort of compare, conceptually, that data with genomics and the kind of things …