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… bit confusion about what a CSP is as opposed to other different kinds of federal grants like through NIH or NSF … genomes. Fungal plant, algal genomes, a lot of effort goes into generating these data sets. There’s a lot of manual … really help improve our annotation. So a lot of effort goes into these, I’m going to call them products for lack of a …
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… always wanted to write a book but it’s really hard to break into that area. I mean you have to secure an agent and … let us know if you want to start somewhere else. You go into this in the book but can you share with listeners what … bit of an unusual kid too because I was born with a lot of different birth defects of my skeletal system. So I was …
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… and you can still make more of it, then you start going into human trials or animal trials first, and going through … in ourselves and every living thing that we know of with cells, and so… So you can think of DNA as maybe being … easy enough? DAN: Well, it is and it isn’t. It depends on different systems of secondary metabolism and the things …
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… episode with her in the near future where we can dive into that. And I’m also dying to talk in more detail about … Yeah, well, there’s a lot of– there’ s a couple of different schools of thought with that. So some people are … a single cell level against cell lines and against primary cells isolated from patients up to 12 markers at a time. And …
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… marine natural products chemist, Richard Moore, and get into seaweed, robots, algae, and biocatalysis — and he makes … him? I know a lot of people sort of veer off and go into different directions. Brad: Absolutely. You know, my father … or they can store that chemical – or they can store the cells, as well. And so we’re hoping initially to be able to …
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I wanted to start, maybe just by asking you how did you get into the field of natural products? NANCY: Yeah, that’s a … was finished with the Peace Corps, I decided I wanted to go into international agriculture. I had really changed my … I like with fungi is, because they’re complex, they have different tissues, different structures, different spores. I …
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… all refer to the chemicals that make species unique and different from one another. They are incredibly important to …
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… fungi, plant), media in which they grow, as well as different types of environments (e.g. soil, lake). A wide …
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… small genes assembled to less than 5kb in length, cloned into vector of choice Glycerol stock of sequence verified … small genes assembled totaling 5-10kb in length, cloned into vector of choice Glycerol stock of sequence verified … microbial aggregate, or a specific subset of free-living cells. Extracted DNA may be amplified using whole-genome …
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… quantities of DNA derived from individual environmental cells. The proof of principle study built off earlier … – a symbiont of the green sharpshooter. In 2012, single cells isolated from the microbes found in the oil plume from …
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… expands the global diversity of large and giant viruses. While the microbes in a single drop of water could … large and giant viruses offered the researchers insights into how they might interact with their hosts, and how those … the phylogenetic tree of giant viruses. Metabolic Reprogramming a Common Strategy for Large and Giant Viruses …
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… that a lot of people want to answer again from a very different standpoint or from very different angles, right? … than it is now. Or a little more– yeah, put more rationale into drug discovery by knowing what these things actually do … even in primary metabolism or in certain snips of viruses or something. I don’t know. Then I think making sure …
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