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… been the main driver for secondary metabolism drug discovery. Because we always need new antibiotics. We need new … found in Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you … Catalog of Earth’s Microbiomes. Nature  Biotechnology . 2020 Nov 9. doi: 10.1038/s41587-020-0718-6) The GEM catalog …

… went on to work at a groundbreaking company in the early 2000s called Ecopia, which was a very early genome mining … and he’s doing some amazing research in and around drug discovery, which includes screening methods, genome mining in … at the end: Henry Schares:  https://sim.confex.com/sim/np2023/meetingapp.cgi/Paper/46926 Jen Wurm:  …

… something you’re interested in. OK. I think that should cover most of the government acronyms. You’re on your own … transcripts and more information about all of the topics we cover. OK. Long intro today. We’ll have two discussions. … We don’t want to get a proposal that’s just asking for 20 microbial genomes. That is not a good fit for our annual …

… requires that all work performed in its User Facilities be covered by the User Agreement. … PMO: Frequently Asked …

… cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply …

… natural products by starting out in synthesis and then discovering more-- [LAUGHS] I don't know, practical or … 10 to the negative 9th. Picomolar, 10 to the negative 12th. DAN: Yeah. So very-- BETSY PARKINSON: Very, very-- … receptors. And so they were originally, I think, discovered in E. coli, but we can utilize blast searches or …

… in this hypersaline environment, which can range from 8% to 28% salinity. We have toxic metals, so these concentrations … natural products, and especially if you’re in the drug discovery angle, is to look in industry. But you’re a … Metabolites Collaboratory SMC Workshop Materials from the 2023 JGI Annual Meeting Using the SMC Website API Endpoints …

… metabolomics data, depending on the specific product types covered in the call.    If you have technical questions, we … … Utilization or transfer of any genetic resource may be covered by local, national or international regulation.  …

… research by then-Biosciences scientist Diane Dickel in 2017. In 2019, plant single-cell methods were officially called out … in wild type and cell identity mutants . Dev Cell. 2022 Feb 28. S1534-5807(22)00033-8.doi: …

Antarctic algae need their vitamins; zinc fuels some of … algae rely on dissolved zinc to photosynthesize. Thomas Mock, a marine microbiologist at the University of East … Science Program (CSP) .  Through this collaboration, in 2017, they published the first genome sequence of a …