Search

… the “Non-Ribosomal Peptide Synthetases” or NRPSs. These are enzyme systems that grab amino acids and stick them together … end, we took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  … ended up doing was pursuing with Jacques Ravel, at TIGR, metagenome sequencing, which was very early days for that …

… DAN: Welcome back to Natural Prodcast! This is episode 4! From here on out, for a while, we’re going to be … backbone gene synthases, but having a different decoration enzyme actually could give you something that’s quite … I wish we could predict. I wish we could look at these enzymes and predict, and really place it to structure. …

… genomics research explores new metabolic processes and enzymes that can be applied in biorefineries, production of …

… microbiomes, and using engineered biosynthetic pathways and enzyme systems to do synthetic analoging of some really … by chemical synthesis and make analogs in combination of mutagenesis and direct evolution. Yeah. DAN UDWARY: So it’s … that if you looked at the grant applications for the last 40 years for studying biosynthetic pathways, all of them …

… in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and … uncover patterns and relationships in complex genomic and metagenomic data. … Communications , Volume 5 Issue 1. Wittmers, F. et al (2024) “ Non-photosynthetic lineages sibling to Cyanobacteria …

… global diversity of alternative genetic codes (Science 2014), unearthing hundreds of thousands of new viral genomes … Unraveling the functional dark matter through global metagenomics. Nature . 622(7983):594-602. Camargo AP. et al. … (2018) Programmed DNA destruction by miniature CRISPR-Cas14 enzymes. Science 362(6416):839-842. Duerkop BA, et al. …