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… … DAN: You’re listening to the US. .Department of Energy Joint … have no extra genes hanging around, they still dedicate 20-30% of their genome to secondary metabolism. So it’s very … system. [ Go here to learn more about Cameron Currie’s metagenomics research, enabled in part by JGI’s Community …
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… … DAN UDWARY: You’re listening to the Department of Energy … all these 120 genomes, and each of them have– I don’t know– 30 gene clusters or so. So I think I spent two years only … that easily can identify secondary metabolite pathways in metagenomes, which is still hard to do. We are mining a lot of …
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… … Dan Udwary: You’re listening to the Department of Energy … that I was exchanging with people. So I think I wrote 3,000 emails in the course of one and a half year while … episode, we talked about genome mining through some metagenome associated genomes. And yes, antiSMASH is …
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U.S. Department of Energy under Contract No. DE-AC02-05CH11231. Accordingly, the U.S. Government retains a nonexclusive, … JGI is not responsible for the contents of any off-site pages referenced. … Disclaimer of Liability … Disclaimer of …
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… … DAN: Hey Marcy! ALISON: Hey Marcy? MARCY: Hello. How’s it … strain and there have been years and years and years about 35-ish years, I think, now, studying Vibrio fischeri and … That is one of the really big frontiers for the next stage of natural product drug discovery I think. Or even …
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… … DAN UDWARY: Hey, everyone. I’ve got a great episode for you … we want to talk a little bit about. It’s sort of early stages. But I think that is emblematic of some of the … underwater. But thankfully that worked out. And I spent 30, 40 years diving all over the world and bringing samples …
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… … DAN: You’re listening to the US Department of Energy Joint … end, we took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart. … ended up doing was pursuing with Jacques Ravel, at TIGR, metagenome sequencing, which was very early days for that …
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… to them. The Committee is chartered to render advice, guidance, and counsel on the effective management and strategic …
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… … DAN UDWARY: Hey everyone and welcome back to a new session … they had the same conserved polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: … by chemical synthesis and make analogs in combination of mutagenesis and direct evolution. Yeah. DAN UDWARY: So it’s …
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… completion of work on all approved proposals within 36 months from the approved start date. Additional time …
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