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DNA Synthesis Program
… the design and synthesis of complex genetic pathways and biosystems. It The program fosters collaboration with U.S. and … functional genomics, focusing on developing genetic systems that can address global energy and environmental … cycle, helping researchers optimize genetic systems. By enabling these cutting-edge approaches, the …
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Microbiome Data Science Team
… A global metagenomic map of urban microbiomes and antimicrobial resistance. Cell . 184(13):3376-3393 Almeida A, et … Genes. Cell 178(5):1245-1259 Nayfach S, et al, (2019) New insights from uncultivated genomes of the global human gut … et al. (2016) Microbiome Data Science: Understanding Our Microbial Planet. Trends Microbiol. 24(6):425-7. …
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Programs & Platform Leads
… of complex biological, earth, and environmental systems for energy and infrastructure security. In … drive innovations that cross the boundaries of the Plant, Fungal, Algal, Microbial, Metagenome, Metabolomics, Secondary Metabolites, …
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Natural Prodcast Episode 23: Aaron Puri
… the genes for and explore the chemistry of quorum sensing systems, specifically the acyl homoserine lactones.  If you … to predict or just understand better the language of microbial cell-cell communication. And he told us about his … DAN: Almost like you know that there is. AARON PURI: It’s a planted question Dan. Yeah. So overall I think what we’re …
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Natural Prodcast Episode 2: The Primer, Part 2
… and ergot alkaloids come from fungi, and Taxol from plants. Plants, fungi, bacteria, archaea, they all have secondary … But… DAN: Yeah, there are a lot of ways to put together carbon molecules. Chemistry is pretty limitless. All right, …
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JGI Portals
… Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic … provides tools for analyzing the functional capability of microbial communities based on their metagenome sequence, in … with functional annotation, taxonomic classification, and microbial host predictions.  …
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Natural Prodcast Episode 13: Francisco Barona Goméz
… for a long time about the evolution and natural products systems. This conversation came about because he challenged … For example, lipids– doesn’t matter if it has one extra carbon or two or one less, at the end of the day, it’s … could be a reasonable number if you are talking about a plant and a microbe interacting very stably. So it makes …
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Natural Prodcast Episode 14: Nigel Mouncey
… I did my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for … with a contract manufacturer to actually have them build a plant for production and fermentation and transfer that … work. And I think as we understand more about regulatory systems that will also help us predict which hosts might be …
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Natural Prodcast Episode 3: The Primer, Part 3
… as anything in this field, and written pretty close to the level of technical detail that I think we’re doing here. If … DAN: Well, it is and it isn’t. It depends on different systems of secondary metabolism and the things that are in … for a long time by many, many bacteria – and fungi and plants. And so that’s the power and the promise of, I guess, …
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Natural Prodcast Episode 18: A CSP Primer
… our eukaryotic genomes, all our eukaryotic genomes. Fungal plant, algal genomes, a lot of effort goes into generating … focus within BER anymore. We really focus on terrestrial ecosystems, but we work in coastal environments, brackish … on that, but maybe you’d want to give a really high level overview of what that looks like? TANJA WOYKE: Yeah. …
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FICUS-NERSC/KBASE
… performance computing (HPC) and data analysis.  The DOE Systems Biology Knowledgebase ( KBase ) integrates systems biology data and tools to help predict biological … work, checking such factors as genome size, polymorphism level, sample quality and availability, etc.   During …
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Natural Prodcast Episode 15: Katherine Duncan
… I want to hear. Kate Duncan: They’re so exciting on so many levels. So first, I mean, all bacteria are everywhere. But … And as a result, there’s been a lot of work on open pond systems and infrastructure and growing microalgae. And to … transcriptomics, metabolomics, and natural products in plants, fungi, and microorganisms. If you want to …
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