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Extracting the Secrets of Secondary Metabolites
… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … to integrate large genetic payloads directly into diverse microbes. Combining CRAGE with CRISPR provides researchers … of the biosynthetic gene clusters that produce them. The Impact Secondary metabolites are microbial compounds …
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Natural Prodcast Episode 9: Roger Linington
… back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser … of areas, we would like to do a better job of understanding gas phase reaction mechanisms. We would like to do a better … in basic science. I think we don’t know enough about gas phase chemistry yet. We don’t know enough about …
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Science Programs
… scientists lend their expertise to enhance the scientific impact of user projects, develop cutting edge approaches for and with users, and create computational tools and resources for them. Their concerted efforts help maximize the JGI’s impact in advancing both user science and the DOE science …
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Cataloging the Microbes that Manage the Health of River Systems
Database provides details on river microbes in 90% of US continental watersheds. The Science In … at multiple scales from genes to the community level. The Impact Rivers are transport systems, and their health is …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… about natural products and the science and scientists of secondary metabolism. Welcome back for our second season of Natural Prodcast. This first episode up is … what kinds of gene cluster families are in which kinds of orgasms. And so we have all of that information. We have …
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Cultivating Symbiotic Antarctic Microbes
Nanohaloarchaeota cultures reveal they are symbionts and not free-living organisms. The Science Researchers … free-living organisms as had been originally thought. The Impact The Antarctic lakes are a “treasure trove” of unknown microbes that play critical roles in environmental processes …
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Natural Prodcast Episode 3: The Primer, Part 3
Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hey there. This is Dan again, and … is here ) so you understand what’s happened so far in the conversation between me and Alison. In the previous episodes … effects. ALISON: Yeah, I guess you’d use something like a gas chromatographer. Yeah. DAN: Yeah. So that involves …
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Natural Prodcast Episode 23: Aaron Puri
… another episode of Natural Prodcast. Right now I’m working on this the afternoon of the day I’m due to release it, … of these bacteria that eat methane, so they can use methane gas as their sole source of carbon and energy. And it was … ecology community to be able to better predict how their microbes are interacting with each other from sequence …
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Stepping on the Gas to a Circular Economy: Accelerating Development of Carbon-Negative Chemical Production from Gas Fermentation
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Plant-Microbial Interactions Group
… associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and associated viruses that all contribute to a dynamic ecosystem. We are interested in how … (low nitrogen or low phosphorus), and how cell identity impacts this response. We will eventually construct a …
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Marine Microbe Contains Multitudes
A deep dive into microbial genomics reveals one bacterial species is made of four ecologically distinct … In the ocean’s North Pacific Subtropical Gyre, microbes tend to stay localized at different depths. But … oceanic depths and relying on different ways of living. The Impact Microbes help regulate the global carbon cycle — …
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Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale
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