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Natural Prodcast Episode 17: Cassandra Quave
… things, because a lot of what we do at JGI in terms of the sequencing that we do is very people-disconnected, and … to understand more about plant natural products? We have sequencing facilities, DNA synthesis, metabolomics. Where do … us, we want to hear from you. We have projects in genome sequencing, DNA synthesis, transcriptomics, metabolomics, …
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Natural Prodcast Episode 18: A CSP Primer
… does all kids of things around nuclear security, energy production, and scientific research, especially at US … Science program. It used to actually stand for Community Sequencing Program. Also CSP, same acronym. But as JGI, as a … you have questions about project relevance or experimental protocols, contact Deputy for User Programs, Tanja Woyke , …
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Natural Prodcast Episode 19: Bill Fenical
… really put the chemistry into the ecological experimental protocols. So that took about 15 years. Of course, at some … that could afford to do all of the complex biology and production that we couldn’t do. So 2021, we have two drugs …
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Natural Prodcast Episode 20: Brian Bachmann
… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … it was a big deal. And you really had– I mean, the whole sequencing endeavor, had a cost, how much blood, sweat, and … that you had the right cluster before you sent it out for sequencing. BRIAN BACHMANN: That’s right. And then just– and …
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Secondary Metabolites Program
… and nutrient acquisition. However, secondary metabolite production is often not fully realized under standard … We have developed Regulon Identification by in vitro-sequencing (RIViT-seq) to identify RNA polymerase-sigma … We are also utilizing DNA-Affinity Purification (DAP) sequencing to express hundreds of transcription factors and …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… really the same kind of thing. Before the age of genome sequencing, we had to basically break up the pieces of DNA … And you would scan those pieces by hybridization or maybe sequencing if you were rich enough. [CHUCKLES] And once you … working in Aspergillus parasiticus . Yeah, so we were sequencing the pieces of that and trying to understand that …
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FICUS-NERSC/KBASE
… plan is written into a Statement of Work document. … For sequencing projects, once work is under way, raw sequence … in publication of results. … Submission … More on Sequencing Projects …
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Special Initiatives & Programs
Overview The JGI provides sequencing, synthesis, and targeted metabolomics support for … a core facility instead. Proposals may not exceed 10 Tbp sequencing, 500 kbp synthesis, and 200 polar/500 nonpolar … critical cost barriers to sustainable, economically viable production of bio-based products and advanced biofuels. The …
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Natural Prodcast Episode 14: Nigel Mouncey
… into piloting and to finally get things into commercial production. So the full stretch of things. Full stretch all … NIGEL MOUNCEY: Oh, sure. I think our legacy obviously is in sequencing.  DAN: Of course.  NIGEL MOUNCEY: Sequencing the wazoo out of anything that’s relevant to the …
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Microbiome Data Science Team
… other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … (Nature 2019). Other projects in the group include the sequencing and comparative analysis of thousands of archaeal … et al. (2014) Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains. PLoS Biology …
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Natural Prodcast Episode 22: Alison Narayan
… [project] with JGI, how many flavin monooxygenases are you sequencing, sort of along that vein, of if you have one or … guess with along that line, with JGI, like how many are you sequencing currently? ALISON NARAYAN: Yeah. So– yeah, with …
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User Programs
For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … with DOE mission-relevant projects that call for expansive sequencing, synthetic biology and metabolomics capabilities … Letters of Intent. Proposals may include synthetic biology, sequencing and metabolomics. Proposals may include synthetic …
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