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… DAN: You’re listening to the US Department of Energy Joint … DNA sequence – sequences for the genes that code for the proteins that produce secondary metabolites. Do you recognize this? DNA 🡺 RNA 🡺 Protein ALISON: This is central dogma. DNA to RNA to … Episode Transcript …

… DAN: All right. Welcome back to Natural Prodcast. I did it. … bind similar ligands. And so one of-- DAN: OK. The similar proteins are going to bind similar molecules. Yeah, OK. … so that thioesterase at the end of this large multimodular protein allows for release from the DNA, either as a …

… Knockout experiments showcase potential for engineering bioenergy crops The Science … National Laboratory (BNL) led a team that  identified a protein , PtrbHLH011, within poplar involved in plant … for Functional Nanomaterials (CFN), National Synchrotron Light Source (NSLS-II), the Molecular Foundry and the Joint …

… DAN: Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … easy to search for because there are patterns of domains, protein domains that you look for. And if you find those all …

… DAN UDWARY: Hey everyone and welcome back to a new session of … or you could look at metabolism markers like phosphoprotein S6. So if there is a perturbagen present– DAN … encyclopedia of enzymes at Aldridge that I could use to buy green uricase or “Wittig-ase” or whatever I was looking for. …

… Dan Udwary: You’re listening to the Department of Energy … with sequence similarity, either we just looked at which protein domains are in a gene cluster or we did sequence … are a few other efforts maybe that are out there and doing slightly different approaches, but antiSMASH has become the I …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore the vast and … The Microbial Program focuses on using advanced sequencing technologies to … and single cells. This effort uncovers novel genes, protein families, and pathways, enhancing our understanding …

… DAN: You’re listening to the US Department of Energy Joint … right? That’s the flavor of monoterpenoids. The very light natural product that gives you this fresh scent of the … So, we were essentially using brute force to isolate the proteins. The proteins are the biological version of the …

… The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the … The DNA Synthesis Program plays a central role in advancing functional genomics, … Genome to Enzymes and Pathways focuses on discovering and characterizing enzymes …