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… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hey there. This is Dan again, and you’re … and actually get to the DNA sequence – sequences for the genes that code for the proteins that produce secondary …

… for you here today. We got the opportunity to talk to one of the real legends of natural products, Professor Bill … working with him on as an exploration into the secondary metabolism of some more novel marine bacteria. You know, I … bacteria. Do you believe that? I mean, glucose is the carbohydrate component of media. So we went back and said, I …

… uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … govern ecosystem processes. This research provides insights into microbial diversity and metabolic potential, with … drive innovations that could advance our understanding of Earth’s ecosystems. …

… about natural products and the science and scientists of secondary metabolism. Natural products, secondary metabolites, and … research, “Natural Prodcast” serves as an important line of communication to the scientific community. Host Dan …

… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … advances in management, processing and visualization of “big data,” and artificial Intelligent/machine learning … discoveries and catalyzing a major transition of biology into data science.  Research in the Kyrpides group focuses …

… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … associated with microeukaryotes, enhances our understanding of terrestrial biogeochemical cycling and inter-organismal … microorganisms, by sequencing large populations of bacteria and archaea in their natural environments using …

… DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I wanted to tell … also dying to talk in more detail about the JGI Secondary Metabolism Collaboratory , which is the big huge monster … could be called semisynthesis. So you can knock out an acyltransferase and then use a free hydroxyl group and do some …

… Data produced and released by the US Department of Energy (DOE) Joint Genome Institute (JGI) are subject to … the need to have a limited and time-sensitive protection of certain types of data to support their use by those generating data. The … PIs or co-PIs) who wish to include use-restricted data in publications, or who wish to redistribute data in any way …

… for researchers to request the capabilities and expertise of both the Joint Genome Institute and the Molecular Foundry … challenges in the sourcing, recovery, and utilization of critical minerals and materials. For accepted proposals, … provides customized analysis, the JGI also participates in publication of results. Go here for additionial information, …

… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … Successful applications will focus on high-risk/high-payoff proposals within the focused topic areas that can be … provides customized analysis, the JGI also participates in publication of results. …